What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Zoryve (Roflumilast)
Prescription Required
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Product Details
Description
Zoryve (roflumilast) cream is used topically to treat patients who are at least 6 years old with plaque psoriasis.
Zoryve is available in 60-gram tubes that contain 3 mg of roflumilast per gram.
Fact Table
Formula
C17H14Cl2F2N2O3
License
US FDA
Bioavailability
79% (oral)
Legal status
Prescription only (Rx)
Chemical Name
3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide
Elimination half-life
17-30 hours
Dosage (Strength)
0.3% topical cream
Pregnancy
Consult a doctor
Brands
Zoryve
Protein binding
99%
PubChem CID
446076
MedlinePlus
a610014
ChEBI
CHEBI:83419
ATC code
D11AH07
DrugBank
DB01656
KEGG
D10144
Routes of administration
Topical
Directions
Use Zoryve as directed by the prescribing doctor. The recommended dose is to apply to the affected areas of the skin once a day.
Do not get the cream in the eyes, mouth, or vaginal areas.
Keep Zoryve cream stored between 20°C and 25°C (68°F and 77°F) and away from children’s reach.
For additional instructions for use, refer to the medication guide that accompanies the prescription.
If you have any questions or concerns, talk to your or your child’s doctor or pharmacist.
Ingredients
The active ingredient in Zoryve is roflumilast.
Inactive ingredients include ceteareth-10 phosphate, cetearyl phosphate, cetostearyl alcohol, diethylene glycol monoethyl ether, hexylene glycol, isopropyl palmitate, methylparaben, propylparaben, purified water, sodium hydroxide, and white petrolatum. Hydrochloric acid may be added for pH balance.
Contraindications
Patients with moderate to severe liver impairment should not use Zoryve cream.
Cautions
- Before you or your child begins treatment with Zoryve, tell the prescribing doctor about:
- All the prescription and over-the-counter medications you or your child takes
- Your or your child’s allergies
- Your or your child’s current health problems and past medical history
- Your or your child’s pregnancy or breastfeeding status
Side Effects
Diarrhea, headache, problems with sleep, application site pain, upper respiratory tract infections, and urinary tract infections are common Zoryve cream side effects. However, other side effects may also occur.
Immediately tell your or your child’s doctor about any side effects that bother you or your child or side effects that won’t go away.
You can buy Zoryve cream right here!
Reference
Zoryve cream. Westlake Village, CA: Arcutis Biotherapeutics, Inc.; 2024.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 14188
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