Description
Chemical Name: FINASTERIDE (fi-NAS-teer-ide)
PROPECIA(Finasteride) is a medication prescribed to treat and prevent male pattern baldness in male patients.
Male pattern baldness (androgenetic alopecia) typically occurs in adults over the age of 18. In men with this condition, the scalp contains hair follicles with an increased amount of receptors for dihydrotestosterone (DHT) compared to those without male pattern baldness. DHT receptors often increase with age.
PROPECIA works by lowering the amount of circulating DHT, preventing the destruction of hair follicles. PROPECIA is a 5-alpha-reductase inhibitor and works by preventing enzyme 5-alpha-reductase from converting testosterone to DHT.
PROPECIA may take several weeks or months to begin showing a noticeable effect. PROPECIA must be taken every day to work effectively.
Directions
The normal directions are to take 1 mg by mouth once daily with or without food.
Take PROPECIA exactly as prescribed by your doctor.
Ingredients
The active ingredient in PROPECIA is finasteride.
Finasteride 1 mg is the name for generic PROPECIA.
Fact Table |
Formula |
C23H36N2O2 |
License |
US FDA |
Bioavailability |
65% |
Legal status |
US: RX Only |
Chemical Name |
Finasteride |
Elimination half-life |
Adults: 5–6 hours Elderly: Greater than 8 hours |
Dosage (Strength) |
1mg (28, 56, or 84 tablets) |
Pregnancy |
Consult a doctor |
Brands |
Propecia, Proscar |
Protein binding |
90% |
PubChem CID |
57363 |
MedlinePlus |
a698016 |
ChEBI |
5056 |
ATC code |
G04CB01 |
DrugBank |
DB01216 |
KEGG |
D00321 |
Routes of administration |
By mouth |
Cautions
PROPECIA is not indicated for the treatment or prevention of baldness in women or children.
Pregnant women should not handle PROPECIA tablets because they can absorb through the skin and cause birth defects.
Use with caution if you have a history of hepatic impairment, as PROPECIA is metabolized extensively in the liver.
Side Effects
The most common adverse effects that happen when taking PROPECIA include:
Speak to your doctor or pharmacist for a full list of side effects that apply to you.
References
- Propecia [package insert]. Whitehouse Station, NJ: Merck; 2010.
- Male Pattern Baldness, Healthline, September 25th, 2017. Retrieved May 2020.
Frequently Asked Questions about Propecia (Finasteride)
Does Propecia regrow hair?
Propecia, the brand name for finasteride, does not directly regrow hair. However, it allows your hair follicles the ability to regrow by reducing the amount of DHT circulating through your body. Significant increases in hair count at both 6 and 12 months have been reported in men treated with finasteride.
How long does Propecia take to work?
You should notice a benefit starting after 3 months of consistent use. However, for visual effects such as the thickening and strengthening of miniaturized hairs, it takes up to 6-12 months.
What is the long-term side effect of Propecia?
Long-term side effects include depression and anxiety, and they can occur even after a person stops taking it. Persistent erectile dysfunction that continued for an average of about 1,350 days after stopping treatment has also been reported.
Can women use Propecia?
Finasteride is not approved to treat hair loss or thinning hair in women. However, providers sometimes use finasteride for women off-label, especially for post-menopausal women when topical minoxidil and oral spironolactone have been ineffective.
Is Propecia over the counter?
Propecia and all finasteride tablets are prescription only, which means you cannot buy the drug over the counter.
Does Propecia decrease testosterone?
Taking Propecia does not lead to a decrease in testosterone production. While it inhibits the conversion of testosterone to DHT, it does not directly affect testosterone production in the testes.
Is it OK to take finasteride for life?
There have been long term scientific studies of finasteride use, for five years, seven years and even 10 years. These studies found no significant consequences of taking finasteride long term.
What is the success rate of Propecia?
One study shows that 83% of men taking Propecia did not experience any more hair loss since the start of the prescription. Furthermore, 66% of the men noticed that they had regrowth.
Does Propecia cause ED?
Common side effects of Propecia include a reduced sex drive and erectile dysfunction.
Does Propecia cause weight gain?
There are some rare cases of people who develop unexplained increase in abdominal fat and weight gain while taking Propecia. However, the majority of the published medical evidence does not support weight gain for the majority of users of finasteride.
About Dr. Conor Sheehy (Page Author)
Dr. Sheehy (BSc Molecular Biology, PharmD) works a clinical pharmacist specializing in cardiology, oncology, and ambulatory care. He’s a board-certified pharmacotherapy specialist (BCPS), and his experience working one-on-one with patients to fine tune their medication and therapy plans for optimal results makes him a valuable subject matter expert for our pharmacy. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 1750