What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Zorvolex (diclofenac)

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Brand

Zorvolex (diclofenac)

Prescription Required

Strength
Qty
18mg
35mg

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  • Product Details

    Description

    Your doctor may prescribe Zorvolex for the treatment of mild to moderate pain. It is an NSAID and should be used for as short of a time as possible to reduce the risk of side effects.

    Fact Table

    Formula

    C14H11Cl2NO2

    License

    US FDA

    Bioavailability

    50–60%

    Legal status

    Rx-Only

    Chemical Name

    Diclofenac

    Elimination half-life

    1.2–2 h

    Dosage (Strength)

    18mg, 35mg

    Pregnancy

    Consult Doctor

    Brands

    Zorvolex

    Protein binding

    More than 99%

    PubChem CID

    3033

    MedlinePlus

    a689002

    ChEBI

    47381

    ATC code

    D11AX18

    DrugBank

    DB00586

    KEGG

    D07816

    Routes of administration

    By mouth, rectal, intramuscular, intravenous, topical

    Directions

    The usual dosage is 18-35 mg by mouth once daily with food. Do not take longer than prescribed.

    Ingredients

    The active ingredient is diclofenac.

    Interactions

    Tell your pharmacist and doctor if you are taking any of the following:

    • Abrocitinib
    • Acemetacin
    • Aminolevulinic Acid
    • Apixaban
    • Bemiparin
    • Cyclosporine
    • Dabigatran Etexilate
    • Deferiprone
    • Edoxaban
    • Enoxaparin
    • Heparin
    • Ketorolac
    • Lithium
    • Loop Diuretics
    • Macimorelin
    • Methotrexate
    • Mifamurtide
    • Nonsteroidal Anti-Inflammatory Agents
    • Nonsteroidal Anti-Inflammatory Agents
    • Phenylbutazone
    • Pralatrexate
    • Rivaroxaban
    • Salicylates
    • Selective Serotonin Reuptake Inhibitors
    • Sincalide
    • Sodium Phosphates
    • Tenofovir Products
    • Tenoxicam
    • Urokinase
    • Vitamin K Antagonists

    Cautions

    Use caution if you have a history of the following:


    Ask your pharmacist and doctor for a full list of precautions.

    Side Effects

    Common side effects may include:

    • Abdominal pain 
    • Abnormal dreams
    • Acute myocardial infarction
    • Agranulocytosis
    • Alopecia
    • Anaphylaxis
    • Anemia
    • Angioedema
    • Anxiety
    • Aplastic anemia
    • Asthenia
    • Asthma
    • Auditory impairment
    • Back pain 
    • Blurred vision
    • Cardiac arrhythmia
    • Cardiac failure
    • Cerebrovascular accident
    • Change in appetite
    • Colitis
    • Coma
    • Confusion
    • Conjunctivitis
    • Constipation 
    • Coronary thrombosis
    • Cystitis
    • Depression
    • Diaphoresis 
    • Diarrhea
    • Dizziness 
    • Drowsiness 
    • Duodenal ulcer
    • Dyspepsia 
    • Dyspnea
    • Dysuria
    • Ecchymoses
    • Edema 
    • Eosinophilia
    • Eructation
    • Erythema multiforme
    • Esophagitis
    • Exfoliative dermatitis
    • Fever
    • Flatulence 
    • Fluid retention
    • Flushing
    • Fulminant hepatitis
    • Gastric ulcer
    • Gastritis
    • Gastrointestinal hemorrhage
    • Gastrointestinal inflammation
    • Gastrointestinal perforation
    • Glossitis
    • Hallucination
    • Headache 
    • Heartburn
    • Hematemesis
    • Hematuria
    • Hemolytic anemia
    • Hepatic failure
    • Hepatic necrosis
    • Hepatitis
    • Hepatotoxicity
    • Hyperglycemia
    • Hypertension 
    • Hypotension
    • Increased liver enzymes
    • Increased serum alanine aminotransferase 
    • Increased serum aspartate aminotransferase
    • Increased serum creatinine 
    • Infection
    • Insomnia
    • Interstitial nephritis
    • Jaundice
    • Leukopenia
    • Limb pain 
    • Lymphadenopathy
    • Malaise
    • Melena
    • Meningitis
    • Musculoskeletal pain 
    • Nausea 
    • Necrolysis
    • Nervousness
    • Oliguria
    • Palpitations
    • Pancreatitis
    • Pancytopenia
    • Paresthesia
    • Peptic ulcer
    • Pneumonia
    • Polyuria
    • Prolonged bleeding time
    • Proteinuria
    • Pruritus 
    • Purpuric disease
    • Rectal hemorrhage
    • Renal failure syndrome
    • Renal function abnormality
    • Renal papillary necrosis
    • Respiratory depression
    • Seizure 
    • Sepsis
    • Sinusitis 
    • Skin photosensitivity
    • Skin rash
    • Stevens-Johnson syndrome
    • Stomatitis
    • Syncope
    • Tachycardia
    • Thrombocytopenia
    • Tinnitus
    • Toxic epidermal 
    • Tremor
    • Upper abdominal pain 
    • Urticaria
    • Vasculitis
    • Vertigo
    • Vomiting 
    • Weight changes
    • Xerostomia

    References

    Zorvolex. Philadelphia, PA: Iroko Pharmaceuticals, LLC; 2013.


    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 13634

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