Ziextenzo (Pegfilgrastim)

What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

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Prescription Required

  • Product Details

    Description

    Ziextenzo (pegfilgrastim-bmez) is a medication prescribed to lower the chances of getting infections with a high fever in patients who have certain types of cancer and are receiving strong anti-cancer drugs that can cause a significant chance of severely low neutrophil counts (a certain type of white blood cell) with fever.

    Ziextenzo 6 mg/0.6 mL is available in single-dose prefilled syringes for injection underneath the skin.

    Fact Table

    Formula

    C845H1343N223O243S9

    License

    US FDA

    Bioavailability

    60-70%

    Legal status

    Prescription only

    Chemical Name

    Pegfilgrastim

    Elimination half-life

    15-80 hours

    Dosage (Strength)

    6 mg/0.6 mL

    Pregnancy

    Consult a doctor

    Brands

    Neulasta, Nyvepria, Ziextenzo, Lapelga

    Protein binding

    N/A

    PubChem CID

    91942286

    MedlinePlus

    a604002

    ChEBI

    63718

    ATC code

    L03AA13

    DrugBank

    DB00019

    KEGG

    D06464

    Routes of administration

    Subcutaneous

    Directions

    Your healthcare provider will determine an appropriate treatment plan for you, including the Ziextenzo dose. You or your caregiver shall also receive training on how to store, prepare, administer, and discard Ziextenzo properly. For further instructions for use, refer to the medication guide that comes with your prescription.

    Do not share needles or syringes with others.

    Talk to your healthcare provider or pharmacist if you have any questions or concerns.

    Ingredients

    The active ingredient in Ziextenzo is pegfilgrastim.

    Contraindications

    Patients with an allergy to pegfilgrastim or filgrastim should not receive Ziextenzo.

    Cautions

    • Before you begin treatment with Ziextenzo, talk to your healthcare provider about:
      • All the prescription and over-the-counter medications you take
      • Your allergies
      • Your current health problems and past medical history
      • Your pregnancy or breastfeeding status
    • Ziextenzo may be associated with causing the following:
      • Potentially fatal splenic rupture
      • Acute respiratory distress syndrome
      • Allergic reactions that may be severe
      • Sickle cell crises
      • Inflammation and damage to the part of the kidney that filters the blood
      • High white blood cell counts
      • Low platelet levels
      • Capillary leak syndrome
      • Tumor growth stimulatory effects on cancerous cells
      • Myelodysplastic syndrome and acute myeloid leukemia in patients who have breast and lung cancer
      • Inflammation of the aorta

    Side Effects

    Bone pain and pain in the arms and legs are the most common side effects of Ziextenzo. However, other side effects may also occur. Immediately inform your healthcare provider of side effects that bother you or won’t go away.

    You can buy Ziextenzo injection here.

    Reference:

    Ziextenzo. Princeton, NJ: Sandoz Inc.; 2023.




    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 14445

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