Description
Yaz Plus (drospirenone/ethinyl estradiol/levomefolate) is a medication often prescribed to prevent pregnancy. It also treats premenstrual dysphoric disorder (PMDD) and moderate acne for those above 14 years who also want birth control and have started their menstrual period. It may also improve folate levels.
Fact Table |
Formula |
C24H30O5 |
License |
Approved by the US FDA |
Bioavailability |
76% |
Legal status |
Rx-only |
Chemical Name |
Drospirenone, ethinyl estradiol, and levomefolate calcium |
Elimination half-life |
30-36 hours |
Dosage (Strength) |
28 days |
Pregnancy |
Category X (not to be used during pregnancy) |
Brands |
Yaz Plus |
Protein binding |
95% |
PubChem CID |
102372 |
MedlinePlus |
007793 |
ChEBI |
16380 |
ATC code |
G03AA12 |
DrugBank |
DB01321 |
KEGG |
D04499 |
Routes of administration |
Oral |
Directions
Yaz Plus comes in a package containing 28 film-coated tablets - 24 active pink tablets each containing 3 mg of drospirenone, 0.02 mg of ethinyl estradiol, and 0.451 mg of levomefolate, and 4 inert light-orange tablets with 0.451 mg of levomefolate.
The recommended dose is one tablet taken orally at the same time each day. The tablets should be swallowed whole with or without food. Yaz Plus pill's effectiveness is greatly improved when taken consistently and correctly.
Ingredients
The active ingredients in Yaz Plus are drospirenone, ethinyl estradiol, and levomefolate.
Contraindications
Discuss your medical history with your doctor. Do not take Yaz Plus if you are allergic to drospirenone, ethinyl estradiol, levomefolate, or any of the other ingredients in Yaz Plus.
Cautions
- Before you start taking Yaz Plus, inform your doctor:
- About any medications you are currently taking, especially those that may affect the effectiveness of Yaz Plus like certain HIV medications, certain seizure medications, or the herb St John's Wort.
- About any medical conditions you have, including high blood pressure, diabetes, high cholesterol, or obesity.
- If you smoke and are over 35 years old.
- If you have a history of blood clots or strokes.
- If you are pregnant or planning to become pregnant. Yaz Plus can cause harm to your unborn baby.
- If you are breastfeeding or plan to breastfeed. Yaz Plus may reduce the quantity and alter the composition of breast milk.
- Be aware that Yaz Plus doesn't protect against sexually transmitted diseases, including HIV/AIDS.
- Yaz Plus can cause hyperkalemia, a condition characterized by high potassium levels. Check with your doctor if you are on other medications that can increase potassium levels.
- Yaz Plus can cause blood clots, which can lead to serious conditions like deep vein thrombosis, pulmonary embolism, stroke, or heart attack. Contact your doctor immediately if you experience sudden blindness, chest pain, difficulty breathing, unusual headache, or weakness or numbness in your arms or legs.
Side Effects
The most common Yaz Plus side effects include nausea, vomiting, headache, bloating, breast tenderness, weight changes, and changes in menstrual periods. If you experience any severe or persistent side effects, reach out to your doctor immediately.
For those wanting to buy Yaz Plus, it can be obtained from an accredited online pharmacy, provided you have a valid prescription.
References:
- Yaz Plus Prescribing Information. Bayer HealthCare Pharmaceuticals Inc.; 2020.
- Yaz Plus (Drospirenone/ Ethinyl Estradiol/ Levomefolate) Important Safety Information. Accessed July 22, 2023.
About Dr. Gerardo Sison (Page Author)
Dr. Sison graduated with honors from the University of Florida. He began his career in pharmacy counseling patients in a community setting and later served in hospitals and clinics. He has also worked in medication therapy management services. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 13913