Xolair (Omalizumab)
What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
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Prescription Required
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Product Details
Description
Xolair is an injectable medication used to treat the following conditions:
- Persistent asthma
- Chronic rhinosinusitis with nasal polyps
- Hives that are spontaneous and recurring
Fact Table
Formula
C6450H9916N1714O2023S38
License
EU EMA, US DailyMed
Bioavailability
62%
Legal status
Rx-Only
Chemical Name
Omalizumab
Elimination half-life
26 days
Dosage (Strength)
-
Pregnancy
Consult with Doctor
Brands
Xolair
Protein binding
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PubChem CID
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MedlinePlus
a603031
ChEBI
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ATC code
R03DX05
DrugBank
DB00043
KEGG
D05251
Routes of administration
Subcutaneous
Directions
Xolair should be administered as directed by your doctor. Talk to your doctor about any questions or concerns you may have.
Your doctor will tell you how much and how often you should receive Xolair injections, depending on the condition being treated.
Ingredients
Omalizumab is the active ingredient contained in Xolair injection.
Contraindications
Xolair should not be administered to patients who are allergic to any of its ingredients.
Cautions
Xolair contains an FDA Boxed Warning regarding the occurrence of anaphylaxis, a serious reaction that can cause tightening of the airway muscles, low blood pressure, fainting, hives, and/or swelling of the tongue or throat. Xolair treatment should be started in a healthcare setting where patients can be observed after its administration and anaphylaxis can be managed if it occurs. Patients should immediately seek emergency care if they develop symptoms of a serious reaction.
- Before you start treatment with Xolair, tell your doctor about:
- All the medications you take
- Your allergies
- Your health conditions and past medical history
- Your pregnancy or breastfeeding status
- Malignancies have been reported in patients treated with Xolair.
- Xolair should not be used to treat an asthma attack or sudden breathing problems.
- Corticosteroids should not be abruptly stopped upon starting treatment with Xolair; they should be gradually decreased.
- Xolair can cause eosinophilic conditions. Patients should seek care if they experience a rash, pulmonary problems, heart problems, and/or nerve problems like nerve pain.
- Xolair should be stopped if patients experience a fever, joint pain, and rash.
Side Effects
Xolair–like any medication–can cause side effects. The most common include–but are not limited to–joint pain, general pain, leg pain, fatigue, dizziness, fracture, arm pain, fever, skin problems, earache, headache, stomach pain, nose bleed, injection site reaction, nausea, common cold, sinus inflammation, upper respiratory tract infection, and cough. Contact your doctor right away if you develop bothersome or persistent side effects.
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Reference:
- Xolair. South San Francisco, CA: Genentech, Inc.; 2023.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 12264
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