Description
Ximino (minocycline hydrochloride) is a medication used for treating pimples and red bumps due to moderate to severe acne vulgaris in people who are at least 12 years old.
Fact Table |
Formula |
C23H27N3O7 |
License |
US FDA, US DailyMed |
Bioavailability |
70–75% |
Legal status |
Rx-Only |
Chemical Name |
Minocycline Hydrochloride |
Elimination half-life |
11–26 hours |
Dosage (Strength) |
45mg, 90mg, 135mg |
Pregnancy |
Not Recommended |
Brands |
Ximino ER |
Protein binding |
70–75% |
PubChem CID |
54675783 |
MedlinePlus |
a682101 |
ChEBI |
50694 |
ATC code |
J01AA08 |
DrugBank |
DB01017 |
KEGG |
D05045 |
Routes of administration |
By mouth |
Directions
Ximino is available in 45 mg, 90 mg, and 135 mg extended-release capsules.
The recommended dose is 1 mg per kg by mouth once daily with or without food for 12 weeks. Ximino Extended-Release Capsules should be swallowed whole.
Ingredients
The active ingredient in Ximino is minocycline hydrochloride.
Contraindications
Discuss your allergies with your doctor. Do not take Ximino if you are allergic to tetracyclines or any of the other ingredients in Ximino.
Cautions
- Before you start taking Ximino, tell your doctor:
- About any medications you take, especially birth control pills, blood thinners, penicillins, antacids, or any medication that contains isotretinoin
- About any medical conditions you have, including liver problems, kidney problems, vision problems, or diarrhea
- If you are going to have surgery with general anesthesia
- If you are pregnant or plan to become pregnant. Ximino may cause harm to your unborn baby.
- If you are breastfeeding or plan to breastfeed. Ximino can pass into your breastmilk and can cause harm to your baby.
- Ximino may cause permanent teeth discoloration in babies or children and should not be taken during the development of teeth.
- Ximino may cause an infection of the intestine. Contact your doctor right away if you experience a fever, cramps, watery diarrhea, persistent diarrhea, or bloody stools. The infection can develop 2 or more months after you quit taking Ximino.
- Ximino can cause liver problems that can become severe. Stop taking Ximino and immediately contact your doctor if you experience confusion, appetite loss, tiredness, diarrhea, yellowing of your eyes or skin, abnormal bleeding, or sleepiness.
- Ximino can cause central nervous system effects, including dizziness, lightheadedness, or vertigo. Contact your doctor right away if you develop persistent headaches or vision problems.
- Ximino can cause a condition called benign intracranial hypertension where there is increased fluid pressure and swelling around the brain. Contact your doctor right away if you develop unusual headaches or vision problems such as blurred or loss of vision.
- Ximino can cause immune system reactions. Contact your doctor right away if you develop a fever, rash, body weakness, or pain in your joints.
- Ximino can cause serious allergic reactions. Seek medical attention immediately if you experience trouble breathing, a rash or hives, sores in your mouth, skin blisters or peeling, swelling of your face, eyes, lips, tongue, or throat, blood in your urine, yellowing of your skin or eyes, fever, dark urine, pain on the right side of your stomach, chest pain, abnormal heart beats, swelling in your legs, ankles, and feet, or darkening of your eyes, gums, nails, scars, skin, and teeth.
- Ximino can make your skin more sensitive to sunlight and light from sunlamps and tanning beds.
- Protect your skin from sun exposure with clothes and sunscreen
- Do not drive or operate machinery until you know how you respond to Ximino.
Side Effects
The most common side effects of Ximino include dizziness, itching, vertigo, headache, and tiredness. If you experience any troublesome or persistent side effects, contact your doctor.
References:
- Ximino Prescribing Information. New Brunswick, NJ: Ohm Laboratories; 2020.
- Ximino (minocycline hydrochloride) Extended Release Capsules. Important Safety Information. Accessed February 3, 2022.
Frequently Asked Questions about Ximino ER (Extended-Release Minocycline)
What is Ximino ER?
Ximino ER is a prescription medication used to treat moderate to severe acne with red bumps and pimples (inflammatory lesions) in people 12 years and older. It belongs to a class of drugs called tetracyclines.
How does Ximino ER work?
It works by reducing bacteria that can contribute to acne breakouts. However, it won't work for non-inflammatory acne (whiteheads, blackheads).
How is Ximino ER taken?
It comes in capsules and is usually taken once daily with or without food. Swallow the capsule whole, don't crush or chew it. Take it with a full glass of water and avoid lying down for at least 10 minutes afterwards.
How long does it take to see results?
It may take several weeks to see improvement in your acne. Be patient and stick with your treatment as prescribed.
What are the common side effects?
Nausea, dizziness, headache, upset stomach, and increased sun sensitivity are common. Tell your doctor if any side effects bother you or worsen.
Can I take Ximino ER if I'm pregnant or breastfeeding?
No, Ximino ER is not recommended during pregnancy or breastfeeding. Talk to your doctor about other acne treatment options if you're pregnant or breastfeeding.
Can I take Ximino ER with other medications?
Some medications can interact with Ximino ER, so tell your doctor about all medications and supplements you're taking, including over-the-counter ones.
Does Ximino ER cure acne?
No, Ximino ER manages acne, but it doesn't cure it. You may need to continue taking it for several months to maintain clear skin.
What should I do if I miss a dose?
Take the missed dose as soon as you remember, unless it's near time for your next dose. Don't take a double dose.
About Dr. Savannah Muncy (Page Author)
Dr. Muncy (PharmD) studied science and education as an undergraduate before attending the Appalachian College of Pharmacy where she completed her PharmD in three years. She is currently using her pharmacy and healthcare expertise to write medical content for clients all around the world. She is focused on delivering the most current, accurate, and engaging information to healthcare professionals and patients. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 13593