What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Xiidra (Lifitegrast Ophthalmic Solution)
Prescription Required
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Product Details
Description
Xiidra (lifitegrast ophthalmic solution) is an eye drop for the treatment of dry eye disease. Xiidra contains lifitegrast 50 mg/mL (5%).
Fact Table
Formula
C29H24F2N2O6S
License
FDA approved in 2016
Bioavailability
Not applicable (localized ocular administration)
Legal status
Prescription only (Rx)
Chemical Name
Lifitegrast Ophthalmic Soluction
Elimination Half-life
Not directly applicable (primarily localized action)
Dosage (Strength)
5% solution
Pregnancy advice
Use only if clearly needed and the benefit outweighs the risk to the fetus. Consult a healthcare provider.
Brands
Xiidra
Protein binding
Not specified
PubChem CID
91889026
ATC code
S01XA25
DrugBank
DB11595
Routes of Administration
Ophthalmic
Directions
Follow the instructions that come with your Xiidra prescription. If you have any questions or concerns about your prescription, talk to your doctor or pharmacist.
The dose is to place one drop in each eye every 12 hours.
Xiidra comes in single-use containers. Each single-use container contains enough solution for use in both eyes.
Wash your hands thoroughly before using Xiidra. Do not touch the tip of the container to any surface, including your eye, in order to prevent injury and contamination.
If you wear contact lenses, take them out before you use Xiidra. You may put them back in after 15 minutes of using Xiidra.
Keep the single-use containers in their foil pouch until you're ready to use them. Immediately use Xiidra after opening. Any unused solution should be disposed of after each dose.
Ingredients
Lifitegrast is the active ingredient contained in Xiidra. The inactive ingredients include sodium chloride, sodium phosphate dibasic anhydrous, sodium thiosulfate pentahydrate, and water for injection. Sodium hydroxide and/or hydrochloric acid are included for pH balance.
Contraindications
Do not use Xiidra if you are allergic to Xiidra or any of its other ingredients.
Cautions
- Before you start treatment with Xiidra, tell your doctor:
- About your allergies
- About your health conditions
- About any medications you use, including other eye drops
- If you wear contact lenses
- If you are pregnant or plan to become pregnant
- If you are nursing or plan to nurse your baby
Side Effects
The most common side effects after using Xiidra were irritation at the instillation site, altered taste, and visual disturbances. If you develop side effects that worry you or won't go away, call your doctor right away.
Reference:
Xiidra (lifitegrast ophthalmic solution), for topical ophthalmic use. East Hanover, NJ: Novartis Pharmaceuticals Corporation; 2020.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13207
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