What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Voquezna (Vonoprazan)

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Brand

Voquezna (Vonoprazan)

Prescription Required

Strength
Qty
10mg
20mg

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  • Product Details

    Description

    Voquezna is a medication prescribed primarily for the treatment of stomach conditions, such as gastroesophageal reflux disease (GERD) and peptic ulcers. As a potassium-competitive acid blocker (P-CAB), it inhibits stomach acid production, which helps alleviate symptoms like heartburn, acid reflux, and ulcers.

    Fact Table

    Formula

    C17H16FN3O2S

    License

    US FDA, PMDA

    Bioavailability

    ~51%

    Legal status

    Prescription only (Rx)

    Chemical Name

    1-[5-(2-Fluorophenyl)-1H-pyrrolo[2,3-b]pyridin-1-ylsulfonyl]-N-methylmethanamine

    Elimination half-life

    7.7 hours

    Dosage (Strength)

    10 mg, 20 mg tablets

    Pregnancy

    Consult a doctor

    Brands

    Voquezna, Takecab

    Protein binding

    80%

    PubChem CID

    44484724

    MedlinePlus

    a622012

    ChEBI

    CHEBI:134722

    ATC code

    A02BC08

    DrugBank

    DB12274

    KEGG

    D09708

    Routes of administration

    Oral

    Directions

    The usual dosage is 10-20 mg, taken orally once daily.

    The duration of treatment varies based on the specific condition for which Voquezna is prescribed.

    Take the medication with or without food. Swallow tablets whole; do not chew, crush, or break them.

    Ingredients

    The active ingredient in Voquezna is vonoprazan.

    Interactions

    The most common drug-drug interactions may include:

    • Abemaciclib
    • Acalabrutinib
    • Alfentanil
    • Amiloride
    • Apalutamide
    • Astemizole
    • Atazanavir
    • Avacopan
    • Axitinib
    • Bedaquiline
    • Bemetizide
    • Bendroflumethiazide
    • Benzhydrocodone
    • Benzthiazide
    • Bosentan
    • Bosutinib
    • Brigatinib
    • Budesonide
    • Bumetanide
    • Canrenoate
    • Canrenone
    • Carbamazepine
    • Cenobamate
    • Ceritinib
    • Chlorothiazide
    • Chlorthalidone
    • Cilostazol
    • Cisapride
    • Citalopram
    • Clindamycin
    • Clopamide
    • Clopidogrel
    • Cobimetinib
    • Codeine
    • Colchicine
    • Conivaptan
    • Crizotinib
    • Cyclopenthiazide
    • Cyclosporine
    • Cyclothiazide
    • Dabrafenib
    • Dasatinib
    • Diazoxide
    • Digoxin
    • Dihydrocodeine
    • Dihydroergotamine
    • Dipyrone
    • Docetaxel
    • Dofetilide
    • Dronedarone
    • Efavirenz
    • Elagolix
    • Entrectinib
    • Enzalutamide
    • Eplerenone
    • Ergotamine
    • Ethacrynic Acid
    • Etozolin
    • Etravirine
    • Everolimus
    • Fentanyl
    • Flibanserin
    • Fosphenytoin
    • Furosemide
    • Hydrochlorothiazide
    • Hydrocodone
    • Hydroflumethiazide
    • Indapamide
    • Ivosidenib
    • Levomethadyl
    • Lomitapide
    • Lorlatinib
    • Lumacaftor
    • Mavacamten
    • Meperidine
    • Methadone
    • Methyclothiazide
    • Metolazone
    • Midostaurin
    • Mitotane
    • Modafinil
    • Nafcillin
    • Nelfinavir
    • Neratinib
    • Nilotinib
    • Olaparib
    • Oxycodone
    • Paclitaxel
    • Pazopanib
    • Phenobarbital
    • Phenytoin
    • Pimavanserin
    • Pimozide
    • Piretanide
    • Polythiazide
    • Primidone
    • Quinethazone
    • Quinidine
    • Quinine
    • Ribociclib
    • Rifabutin
    • Rifampin
    • Rifapentine
    • Roflumilast
    • Ruxolitinib
    • Sirolimus
    • Sonidegib
    • Spironolactone
    • St John's Wort
    • Sufentanil
    • Sunitinib
    • Tacrolimus
    • Tamoxifen
    • Telotristat Ethyl
    • Temsirolimus
    • Thioridazine
    • Tolvaptan
    • Torsemide
    • Tramadol
    • Triamterene
    • Trichlormethiazide
    • Warfarin
    • Xipamide
    • Zanubrutinib

    Cautions

    Before beginning Voquezna, inform your doctor if you have any history of liver disease, osteoporosis, or low magnesium levels.

    Pregnant or breastfeeding women should consult with their healthcare provider before using Voquezna, as its safety during pregnancy and breastfeeding is not fully known.

    Avoid using Voquezna if you are allergic to vonoprazan or any other ingredients in the medication.

    Side Effects

    The most common side effects of this drug may include:

    • Abdominal distension symptom
    • Abdominal pain
    • Anaphylaxis
    • Candidiasis, Vulvovaginal
    • Constipation
    • Diarrhea
    • Gastritis
    • Headache
    • Hypertension
    • Indigestion
    • Liver failure
    • Nausea
    • Nasopharyngitis
    • Respiratory
    • Stevens-Johnson syndrome
    • Taste sense altered
    • Toxic epidermal necrolysis
    • Tubulointerstitial nephritis, acute
    • Urinary tract infectious disease

    References

    Voquezna [package insert]. Buffalo Grove, IL: Phathom; 2023.



    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 14895

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