Vizimpro (Dacomitinib)
What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
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Prescription Required
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Product Details
Description
Vizimpro (dacomitinib) is a prescription medication used to treat patients with non-small cell lung cancer that has spread to other parts of the body. It is used as a first-line treatment if tumors have certain types of abnormal epidermal growth factor receptor genes as determined by a test approved by the FDA.
Vizimpro is available in 15 mg, 30 mg, and 45 mg tablets for oral administration.
Fact Table
Formula
C24H25ClFN5O2
License
US FDA, EMA
Bioavailability
80% (approximate)
Legal status
Prescription only
Chemical Name
4-[(3-Ethynylphenyl)amino]-7-methoxy-6-[3-(piperidin-1-yl)propoxy]quinazoline-1-yl]-N-(3-fluorophenyl)acetamide
Elimination half-life
70 hours
Dosage (Strength)
15 mg, 30 mg, 45 mg tablets
Pregnancy
Consult a doctor
Brands
Vizimpro
Protein binding
98%
PubChem CID
24957090
MedlinePlus
a618027
ChEBI
CHEBI:134790
ATC code
L01XE45
DrugBank
DB11707
KEGG
D10643
Routes of administration
Oral
Directions
Take Vizimpro exactly as prescribed by your doctor, who will determine an appropriate Vizimpro dose for you.
Keep Vizimpro tablets stored between 20°C and 25°C (68°F and 77°F) and away from children’s reach.
For further instructions for use, you may refer to the medication guide that comes with your Vizimpro prescription.
Speak with your doctor or pharmacist if you have any questions or concerns.
Ingredients
The active ingredient in Vizimpro is dacomitinib.
Inactive ingredients include lactose monohydrate, microcrystalline cellulose, sodium starch glycolate, and magnesium stearate. The film coating consists of Opadry II® Blue 85F30716 containing: polyvinyl alcohol – partially hydrolyzed, talc, titanium dioxide, macrogol/PEG 3350, and FD&C Blue #2/Indigo Carmine Aluminum Lake.
Contraindications
There are no contraindications listed according to the most recent Prescribing Information.
Cautions
- Before you start taking Vizimpro, inform your doctor of:
- All the prescription and over-the-counter medications you take
- Your allergies
- Your current health problems and past medical history
- Your pregnancy or breastfeeding status
- Vizimpro contains the following warnings and precautions:
- Interstitial lung disease
- Diarrhea
- Skin reactions
- Fetal harm–females of reproductive ability should be advised to use effective contraceptive methods while being treated with Vizimpro and for at least 17 days after taking the last dose of treatment
Side Effects
Diarrhea, rash, nail infection, swelling and sores in the mouth, decreased appetite, dry skin, weight loss, hair loss, cough, and itching are common Vizimpro side effects; however, other side effects may also occur.
Tell your doctor immediately if you have side effects that bother you or won't go away.
Searching for a competitive Vizimpro price? With a valid prescription, you can buy Vizimpro right here!
Reference
Vizimpro. New York, NY: Pfizer Labs; 2020.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 14628
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