Vivelle Dot (Estradiol)

Also Known as Estradot

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  Description

  

  What is VIVELLE DOT (or Estradot)?

  VIVELLE DOT, known as Estradot in the UK, is a female hormone usually given to women who are no longer able to produce the proper amount of hormones such as estrogen. It can help control moderate to severe symptoms of menopause, including hot flashes, night sweats, vaginal dryness and atrophy. VIVELLE DOT, and Estradot, also help reduce the risk of postmenopausal osteoporosis, which is a major health concern for women after menopause.

  VIVELLE DOT Dose and Directions

  The VIVELLE DOT dose is different for each patient. Closely follow the directions on the label. If your VIVELLE DOT dose is different than what’s on the label, do not change it unless your doctor tells you to do so. The amount of medication that you take depends on the strength of the medicine. The medical problem for which you are using the medicine will determine; the number of doses you take each day, the time allowed between doses, and the length of time you take the VIVELLE DOT dose.

  VIVELLE DOT Price

  Buy VIVELLE DOT online for the lowest available price. It's easier to compare VIVELLE DOT price points online than by shopping in stores. In addition, Canada Pharmacy offers a Lowest VIVELLE DOT Price Guarantee so you can be sure you are getting the best VIVELLE DOT Price.

  VIVELLE DOT Coupons

  Sign up with Canada Pharmacy to receive VIVELLE DOT Coupons when they become available. Once available, VIVELLE DOT coupons will be emailed to Canada Pharmacy customers who buy VIVELLE DOT online. At this time there are no VIVELLE DOT coupons offered directly on the website.

  
  

  Fact Table
  Formula	C18H24O2
  License	FDA-approved
  Bioavailability	Transdermal (through skin) bioavailability varies; specific data for Vivelle Dot not readily available but generally considered to be efficient due to the bypassing of first-pass metabolism
  Legal status	Prescription drug in the U.S. and many other countries
  Chemical Name	Estra-1,3,5(10)-triene-3,17ß-diol
  Elimination half-life	Approximately 13 to 20 hours when administered transdermally
  Dosage (Strength)	Transdermal patch: 0.025 mg/day, 0.0375 mg/day, 0.05 mg/day, 0.075 mg/day, 0.1 mg/day
  Pregnancy	Not recommended during pregnancy. Classified as FDA pregnancy category X.
  Brands	Vivelle-Dot, among others
  Protein binding	Approximately 98%
  PubChem CID	5757
  MedlinePlus	a603024
  ChEBI	CHEBI:16469
  ATC code	G03CA03
  DrugBank	DB00783
  KEGG	D00105
  Routes of administration	Transdermal

  Directions

  The dosage for VIVELLE DOT will be different for each patient. Closely follow the directions on the label. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medication that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine

  Cautions

  All estrogen therapies carry risk because they can increase the chances of getting cancer of the uterus (womb). You should report any unusual vaginal bleeding right away while you are taking estrogens. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb).

  Do not use estrogens (with or without progestins) to prevent heart disease, heart attacks or strokes. Using estrogens (with or without progestins) may increase your chances of getting heart attacks, strokes, breast cancer, and blood clots. Using estrogens may increase your risk of dementia (decline in memory and thinking skills).

  VIVELLE DOT (estrogen therapy) should not be used if you:

  • are allergic to CombiPatch or any of its ingredients
  • have unusual vaginal bleeding
  • currently have or have had certain cancers, including cancer of the breast or uterus
  • had a stroke or heart attack in the recent past (for example, in the past year)
  • currently have or have had blood clots
  • currently have or have had liver problems
  • may be pregnant

  To make sure you can safely use VIVELLE DOT, tell your doctor if you have any of these other conditions:

  • high blood pressure, angina, or heart disease
  • high cholesterol
  • liver disease
  • kidney disease
  • asthma
  • epilepsy or other seizure disorder
  • migraines
  • diabetes
  • depression
  • gallbladder disease
  • if you have had your uterus removed (hysterectomy)

  Side Effects

  All medications may cause side effects, but usually patients have no, or minor, side effects. Common side effects of VIVELLE DOT may include:

  • headaches
  • breast tenderness
  • back pain

  Less serious side effects may include:

  • nausea, vomiting, loss of appetite;
  • swollen breasts;
  • acne or skin color changes;
  • decreased sex drive, impotence, or difficulty having an orgasm;
  • migraine headaches or dizziness;
  • vaginal pain, dryness, or discomfort;
  • swelling of your ankles or feet;
  • depression; or
  • changes in your menstrual periods, break-through bleeding

  Serious side effects may include:

  • chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling
  • sudden numbness or weakness, especially on one side of the body
  • sudden severe headache, confusion, problems with vision, speech, or balance
  • pain or swelling in your lower leg
  • abnormal vaginal bleeding
  • pain, swelling, or tenderness in your stomach
  • jaundice (yellowing of the skin or eyes)
  • a lump in your breast

  
  

  Frequently Asked Questions about Vivelle-Dot

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  What is Vivelle-Dot?

  Vivelle-Dot is a skin patch containing estradiol, a form of estrogen. It’s used to treat menopause symptoms like hot flashes, vaginal dryness, and irritation. It can also prevent postmenopausal osteoporosis and treat ovarian disorders.

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  Why is Vivelle-Dot so expensive?

  Brand-name drugs can be costly due to research, testing, and exclusivity. Generic versions are more affordable. Manufacturer savings cards and coupons can help reduce costs.

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  Can Vivelle-Dot cause weight gain?

  Weight gain is not a specific side effect of Vivelle-Dot. However, hormone imbalances can contribute to weight changes.

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  Does Vivelle-Dot cause hair loss?

  Hair loss is not a direct side effect of Vivelle-Dot. It may be related to hormonal imbalances or other factors.

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  What are the benefits of Vivelle-Dot?

  Vivelle-Dot relieves menopause symptoms (hot flashes, vaginal dryness), prevents postmenopausal osteoporosis, and treats ovarian disorders.

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  What is the difference between Climara and Vivelle-Dot?

  Both contain estradiol, but they may have different dosages and release mechanisms. Consult your doctor for personalized advice.

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  Is Vivelle-Dot estrogen only?

  Yes, Vivelle-Dot contains estradiol, which is a form of estrogen.

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  How long does it take for Vivelle-Dot patch to start working?

  Vivelle-Dot starts working once applied. It provides continuous estrogen delivery to manage menopause symptoms.

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  Can you shower with Vivelle-Dot?

  Yes, you can shower while wearing Vivelle-Dot. It’s designed to stay in place during daily activities.

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  How many patches come in a Vivelle-Dot box?

  The number of patches in a Vivelle-Dot box can vary based on the prescribed dosage and duration. Consult your doctor or pharmacist for specifics.

  
  

  IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

  Product Code : 9398

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