Description
Valtrex is a prescription antiviral that can be used to treat the following conditions:
- Cold sores
- Genital herpes
- Herpes zoster
Valtrex can also be used for viral suppression in patients who are positive for HIV.
Valtrex works by incorporating into an important virus enzyme that helps it to replicate. Once incorporated, viral particles cannot reproduce, and the body can suppress the infection. Valtrex does not cure herpes infection, but it can stop symptoms.
Fact Table |
Formula |
C13H20N6O4 |
License |
US FDA |
Bioavailability |
55% |
Legal status |
US: RX Only |
Chemical Name |
Valacyclovir |
Elimination half-life |
- |
Dosage (Strength) |
500mg (42 tablets), 1000mg (42 tablets) |
Pregnancy |
Consult a doctor |
Brands |
Valtrex |
Protein binding |
13-18% |
PubChem CID |
2764 |
MedlinePlus |
a695010 |
ChEBI |
35854 |
ATC code |
J05AB11 |
DrugBank |
DB00577 |
KEGG |
D00398 |
Routes of administration |
By mouth (tablets) |
Directions
The dosage of Valtrex depends on why it is being used:
- Cold sores: Take 2 grams by mouth every 12 hours for one day
- Genital herpes, initial episode: Take 1 gram by mouth twice daily for ten days
- Genital herpes, recurrent episode: Take 500 mg by mouth twice daily for three days
- Suppression of HIV: 500 mg by mouth once daily
Take Valtrex exactly as prescribed by the doctor.
The dose may need to be reduced if you have poor kidney function.
Take each dose with a full glass of water to prevent accumulation in the kidneys.
Ingredients
The active ingredient in Valtrex generic is Valacyclovir.
Interactions
Common drug-drug interactions with this medication may include:
- Cladribine
- Clozapine
- Foscarnet
- Mycophenolate
- Tenofovir
- Theophylline
- Tizanidine
- Varicella vaccine
- Zidovudine
- Zoster vaccine
Cautions
Valtrex should be used with caution in older patients and those with poor kidney function unless directed by your healthcare provider.
Valtrex should not be used for longer than prescribed by your doctor.
Side Effects
Valtrex side effects may include the following:
- Abdominal pain
- Arthralgia
- Decreased hemoglobin
- Dehydration
- Depression
- Diarrhea
- Dizziness
- Dysmenorrhea
- Fatigue
- Fever
- Headache
- Increased liver enzymes
- Increased serum creatinine
- Leukopenia
- Nasopharyngitis
- Nausea
- Neutropenia
- Rhinorrhea
- Skin rash
- Thrombocytopenia
- Vomiting
Tell your doctor if you experience any of the above adverse reactions.
References
- Valtrex [package insert]. Greenville, NC: GlaxoSmithKline; 2008.
Frequently Asked Questions about Valtrex (Valacyclovir)
What is Valtrex (Valacyclovir)?
Valtrex is a prescription medication that contains the active ingredient Valacyclovir. It is primarily used to treat viral infections caused by herpes viruses, including genital herpes, cold sores, and shingles.
How does Valtrex work?
Valtrex works by suppressing the replication of herpes viruses in the body. It is converted into another substance, acyclovir, in the body, which interferes with the virus's ability to multiply and spread.
What conditions does Valtrex treat?
Valtrex is commonly prescribed to treat genital herpes (herpes simplex virus type 2), cold sores (herpes simplex virus type 1), and shingles (herpes zoster). It may also be used in some cases for other viral infections as determined by a healthcare provider.
Is Valtrex effective in preventing the spread of herpes to others?
While Valtrex can help reduce the frequency and severity of herpes outbreaks, it is not a guarantee against spreading the virus to others. Safe sexual practices and using precautions like condoms are still essential to minimize the risk of transmission.
How should Valtrex be taken?
Valtrex is typically taken by mouth with or without food. The dosage and duration of treatment will depend on the specific condition being treated. It's crucial to follow your healthcare provider's instructions carefully.
Are there any common side effects associated with Valtrex?
Common side effects of Valtrex may include headache, nausea, stomach pain, and dizziness. Serious side effects are rare but can include allergic reactions. Consult your healthcare provider if you experience any unusual symptoms.
Can Valtrex be used to cure herpes infections completely?
Valtrex can help manage and alleviate the symptoms of herpes, but it does not cure the infection. Herpes is a lifelong viral infection, and Valtrex helps control outbreaks and reduce their frequency.
Can Valtrex interact with other medications?
Valtrex may interact with certain medications, so it is crucial to inform your healthcare provider about all the medications, supplements, and herbal products you are taking to avoid potential drug interactions.
Is a prescription required to obtain Valtrex?
Yes, Valtrex is a prescription medication, and you will need to consult a healthcare provider to determine if it is an appropriate treatment for your condition.
Can Valtrex prevent future herpes outbreaks?
Valtrex may help reduce the frequency of herpes outbreaks, but it may not completely prevent them. The effectiveness can vary from person to person.
About Dr. Conor Sheehy (Page Author)
Dr. Sheehy (BSc Molecular Biology, PharmD) works a clinical pharmacist specializing in cardiology, oncology, and ambulatory care. He’s a board-certified pharmacotherapy specialist (BCPS), and his experience working one-on-one with patients to fine tune their medication and therapy plans for optimal results makes him a valuable subject matter expert for our pharmacy. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 1885