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Uceris Rectal Foam (Budesonide)

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Brand

Uceris Rectal Foam (Budesonide)

Prescription Required

Strength
Qty
2mg(14gram Actuation Can)

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  • Product Details

    Description

    Uceris Rectal Foam contains budesonide, a corticosteroid used to treat mild to moderate ulcerative colitis. It is formulated for rectal administration to target inflammation in the lower part of the colon and rectum.

    Budesonide works by reducing inflammation and suppressing the immune response, helping to alleviate symptoms such as rectal bleeding, pain, and diarrhea.

    Fact Table

    Formula

    C25H34O6

    License

    US FDA

    Bioavailability

    10% (rectal foam)

    Legal status

    Prescription only (?)

    Chemical Name

    (11ß,16a)-16,17-[(1-methylethylidene)bis(oxy)]-11,21-dihydroxypregna-1,4-diene-3,20-dione

    Elimination half-life

    2-3.6 hours

    Dosage (Strength)

    2 mg per application (rectal foam)

    Pregnancy

    Consult a doctor

    Brands

    Uceris, Entocort, Pulmicort

    Protein binding

    85-90%

    PubChem CID

    5281004

    MedlinePlus

    a608007

    ChEBI

    CHEBI:3207

    ATC code

    A07EA06

    DrugBank

    DB01222

    KEGG

    D07514

    Routes of administration

    Rectal

    Directions

    Administer twice daily for two weeks and then once daily for the next four weeks.

    Ingredients

    The active ingredient in Uceris Rectal Foam is budesonide.

    Interactions

    Common drug-drug interactions include:

    • Aceclofenac
    • Acemetacin
    • Adagrasib
    • Amiodarone
    • Amprenavir
    • Amtolmetin Guacil
    • Aprepitant
    • Aspirin
    • Atazanavir
    • Avacopan
    • Balofloxacin
    • Bemiparin
    • Berotralstat
    • Besifloxacin
    • Boceprevir
    • Bromfenac
    • Bufexamac
    • Bupropion
    • Carbamazepine
    • Celecoxib
    • Ceritinib
    • Choline Salicylate
    • Cilostazol
    • Cimetidine
    • Ciprofloxacin
    • Clarithromycin
    • Clofazimine
    • Clonixin
    • Cobicistat
    • Conivaptan
    • Cosyntropin
    • Cyclosporine
    • Dabrafenib
    • Darunavir
    • Delavirdine
    • Desmopressin
    • Dexibuprofen
    • Dexketoprofen
    • Diclofenac
    • Diflunisal
    • Diltiazem
    • Dipyrone
    • Dronedarone
    • Droxicam
    • Duvelisib
    • Enoxacin
    • Etodolac
    • Etofenamate
    • Etoricoxib
    • Fedratinib
    • Felbinac
    • Fenoprofen
    • Fepradinol
    • Feprazone
    • Fexinidazole
    • Fleroxacin
    • Floctafenine
    • Fluconazole
    • Flufenamic Acid
    • Flumequine
    • Flurbiprofen
    • Fluvoxamine
    • Fosamprenavir
    • Fosaprepitant
    • Fosnetupitant
    • Gatifloxacin
    • Gemifloxacin
    • Ibuprofen
    • Idelalisib
    • Imatinib
    • Indinavir
    • Indomethacin
    • Itraconazole
    • Ivacaftor
    • Ivosidenib
    • Ketoconazole
    • Ketoprofen
    • Ketorolac
    • Larotrectinib
    • Lefamulin
    • Lenacapavir
    • Letermovir
    • Levofloxacin
    • Levoketoconazole
    • Lomefloxacin
    • Lomitapide
    • Lonafarnib
    • Lopinavir
    • Lorlatinib
    • Lornoxicam
    • Loxoprofen
    • Lumacaftor
    • Lumiracoxib
    • Lutetium Lu 177 Dotatate
    • Macimorelin
    • Maribavir
    • Mavacamten
    • Meclofenamate
    • Mefenamic Acid
    • Meloxicam
    • Mifepristone
    • Morniflumate
    • Moxifloxacin
    • Nabumetone
    • Nadifloxacin
    • Nadroparin
    • Naproxen
    • Nefazodone
    • Nelfinavir
    • Nepafenac
    • Netupitant
    • Niflumic Acid
    • Nilotinib
    • Nimesulide
    • Nimesulide Beta Cyclodextrin
    • Nirmatrelvir
    • Norfloxacin
    • Ofloxacin
    • Olutasidenib
    • Omaveloxolone
    • Oxaprozin
    • Oxyphenbutazone
    • Pacritinib
    • Palbociclib
    • Parecoxib
    • Paritaprevir
    • Pazufloxacin
    • Pefloxacin
    • Phenobarbital
    • Phenylbutazone
    • Piketoprofen
    • Piroxicam
    • Pirtobrutinib
    • Posaconazole
    • Pranoprofen
    • Primidone
    • Proglumetacin
    • Propyphenazone
    • Proquazone
    • Prulifloxacin
    • Ranitidine
    • Ribociclib
    • Ritlecitinib
    • Ritonavir
    • Rofecoxib
    • Rotavirus Vaccine, Live
    • Rufloxacin
    • Salicylic Acid
    • Salsalate
    • Saquinavir
    • Sargramostim
    • Schisandra sphenanthera
    • Sodium Salicylate
    • Somatrogon-ghla
    • Sparfloxacin
    • Sulindac
    • Telaprevir
    • Telithromycin
    • Tenoxicam
    • Tiaprofenic Acid
    • Tolfenamic Acid
    • Tolmetin
    • Tosufloxacin
    • Trofinetide
    • Troleandomycin
    • Tucatinib
    • Upadacitinib
    • Valdecoxib
    • Verapamil
    • Vonoprazan
    • Voriconazole
    • Voxelotor

    Cautions

    Uceris Rectal Foam should be used cautiously in patients with a history of infections, high blood pressure, diabetes, osteoporosis, peptic ulcers, or any other condition that may worsen with corticosteroid use.

    Prolonged use of corticosteroids can suppress the immune system, increasing the risk of infections.

    Side Effects

    Common side effects of this drug include:

    • Acne
    • Angioedema
    • Arthralgia
    • Bleeding from nose
    • Cataract
    • Constipation
    • Cough
    • Cushing's syndrome
    • Dermatitis
    • Diarrhea
    • Dizziness
    • Dyspnea
    • Edema of face
    • Erosive esophagitis
    • Fatigue
    • Fracture of bone
    • Gastroenteritis
    • Headache
    • Hirsutism
    • Hyperglycemia
    • Hypertension
    • Hypersensitivity reaction
    • Hypocortisolism secondary to another disorder
    • Indigestion
    • Leukocytosis
    • Nausea
    • Nasal stinging/burning
    • Oral candidiasis
    • Osteoporosis
    • Peripheral edema
    • Pneumonia
    • Respiratory tract infection
    • Sinusitis
    • Spasm
    • Suppression of adrenal gland
    • Syncope
    • Throat irritation
    • Type 2 diabetes mellitus

    References

    Uceris Rectal Foam [package insert]. Raleigh, NC: Salix Pharmaceuticals; October 2014.



    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 14948

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