What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Uceris (Budesonide ER)
Also Known as Cortiment
Prescription Required
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Product Details
Description
Uceris is a prescription medication for mild to moderate active ulcerative colitis, a form of inflammatory bowel disease (IBD). It belongs to the class of drugs known as corticosteroids, which work by reducing inflammation in the intestines.
The active ingredient in Uceris is budesonide. The drug is formulated to bypass the stomach and work directly in the colon. This localized delivery minimizes systemic side effects often associated with corticosteroid use.
Fact Table
Formula
C25H34O6
License
EU EMA, US DailyMed
Bioavailability
10-20%
Legal status
Rx-Only
Chemical Name
Budesonide
Elimination half-life
2.0-3.6 hours
Dosage (Strength)
9mg
Pregnancy
Consult Doctor
Brands
Uceris ER
Protein binding
85-90%
PubChem CID
40000
MedlinePlus
a608007
ChEBI
3207
ATC code
A07EA06
DrugBank
DB01222
KEGG
D00246
Routes of administration
By mouth
Directions
The dosage is 9 mg by mouth once daily in the morning with or without food.
Ingredients
The active ingredient in Uceris is budesonide.
Interactions
Common interactions include:
- Aldesleukin
- Antacids
- Bile Acid Sequestrants
- Budesonide
- Clofazimine
- Corticosteroids
- Fexinidazole
- Fusidic Acid
Cautions
Tell your healthcare provider if you have a history of liver disease, tuberculosis, or other infections before using Uceris. The medication may suppress the immune system, increasing the risk of infections.
Side Effects
Common side effects may include:
- Abscess
- Acne vulgaris
- Agitation
- Alopecia
- Amnesia
- Anaphylaxis
- Anemia
- Ankle edema
- Arthralgia
- Arthritis
- Asthenia
- Back pain
- Bronchitis
- Bruise
- C-reactive protein increased
- Chest pain
- Confusion
- Constipation
- Dermatitis
- Dermatological disease
- Diaphoresis
- Diarrhea
- Dizziness
- Drowsiness
- Dyspepsia
- Dyspnea
- Dysuria
- Eczema
- Edema
- Emotional lability
- Enteritis
- Epigastric pain
- Erythrocyte sedimentation rate increased
- Eye disease
- Facial edema
- Fatigue
- Fever
- Flatulence
- Flu-like symptoms
- Gastrointestinal fistula
- Glossitis
- Headache
- Hematuria
- Hemorrhoids
- Hirsutism
- Hyperkinetic muscle activity
- Hypokalemia
- Hypertension
- Idiopathic intracranial hypertension
- Increased appetite
- Increased erythrocyte sedimentation rate
- Increased serum alkaline phosphatase
- Insomnia
- Intestinal obstruction
- Intermenstrual bleeding
- Leukocytosis
- Malaise
- Menstrual disease
- Moon face
- Mood changes
- Muscle cramps
- Muscle spasm
- Myalgia
- Nausea
- Nervousness
- Nocturia
- Numbness
- Otic infection
- Oral candidiasis
- Palpitations
- Paresthesia
- Pharyngeal disease
- Phlebitis
- Postoperative infection
- Pulmonary edema
- Purpuric disease
- Pyuria
- Rash
- Rectal hemorrhage
- Redistribution of body fat
- Respiratory tract infection
- Rhinitis
- Seizure
- Serum alkaline phosphatase increased
- Sexual dysfunction
- Sinusitis
- Skin rash
- Sleep disorder
- Stomach ulcer
- Stomach ulcer hemorrhage
- Stroke
- Swelling
- Tachycardia
- Tongue edema
- Tremor
- Upper abdominal pain
- Urinary frequency
- Urinary tract infection
- Vertigo
- Viral infection
- Visual disturbance
- Weight gain
References
- Uceris ER [package insert]. Bridgewater, NJ: Salix Pharmaceuticals; 2020.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13787
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