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What is a Generic Drug?

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The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Tobrex (TobramycIin)

Brand

Tobrex (TobramycIin)

Prescription Required

Strength
Qty
Eye Ointment 0.3%
Eye Drops 0.3%
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  • Related Products & Conditions

  • Product Details

    Description

    Tobrex is a prescription eye medication for the treatment of certain types of eye infections. Eye infections can be viral, bacterial, or fungal. Tobrex is an antibacterial that treats infections from bacteria.

    Tobrex works by blocking the creation of bacterial proteins. Proteins are necessary for life, and blocking their synthesis kills the infective bacteria.

    Fact Table

    Formula

    C18H37N5O9

    License

    EU EMA, US FDA

    Bioavailability

    11.7%

    Legal status

    Rx Only

    Chemical Name

    Tobramycin

    Elimination half-life

    2–3 hrs

    Dosage (Strength)

    0.3%

    Pregnancy

    Consult Doctor

    Brands

    Nebcin, Tobrex, Tobi

    Protein binding

    Not bound

    PubChem CID

    36294

    MedlinePlus

    a682660

    ChEBI

    28864

    ATC code

    J01GB01

    DrugBank

    DB00684

    KEGG

    D00063

    Routes of administration

    IV, IM, inhalation, eye drops/ointment

    Directions

    Take Tobrex for as long as directed by your doctor. Using it for less than the prescribed amount of time may cause the development of bacterial resistance. However, using it for longer than prescribed may also cause this problem.

    The usual dosage is 1-2 drops every four eyes into the affected eyes for mild or moderate infections. For severe infections, the directions are to use every two hours.

    Do not touch the tip of the dropper to the eye as this may cause contamination of the Tobrex bottle.

    Ingredients

    Tobramycin is the active ingredient in Tobrex.

    Store this drug at room temperature and discard it as soon as it reaches the expiration date on the bottle.

    Interactions

    There are no known significant interactions. However, Tobrex should not be used simultaneously as other eye medications.

    Cautions

    Do not wear contact lenses while you are using this product.

    Do not use this drug if you are allergic to aminoglycoside medications.

    Side Effects

    Some of the more common tobramycin side effects may include:

    • Anaphylaxis
    • Conjunctival erythema
    • Erythema multiforme
    • Eyelid edema
    • Eyelid pruritus
    • Hypersensitivity reaction
    • Ocular toxicity
    • Skin rash
    • Stevens-Johnson syndrome


    Tell your doctor and pharmacist if you experience any of the above while taking this drug.

    References

    Tobrex [package insert]. Fort Worth, TX: Alcon Laboratories, Inc.; 2012.


    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 5261

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