What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Temodar (Temozolomide)

Also Known as Temodal

Sezzle
Brand

Temodar (Temozolomide)

Prescription Required

Strength
Qty
5mg
20mg
100mg
180mg
250mg

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using Sezzle

Generic Equivalent - Temodar (Temozolomide)

Prescription Required

Strength
Qty
5mg
20mg
100mg
140mg
250mg

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using Sezzle

  • Product Details

    Description

    Temodar is a prescription chemotherapy medication used in the treatment:

    • Newly diagnosed glioblastoma multiforme (GBM) along with radiation
    • Refractory anaplastic astrocytoma patients who have failed prior treatment


    Temodar works by incorporating cancer cells' DNA and preventing their replication.

    Fact Table

    Formula

    C6H6N6O2

    License

    EU EMA, US FDA

    Bioavailability

    almost 100%

    Legal status

    Rx-only

    Chemical Name

    Temozolomide

    Elimination half-life

    1.8 hours

    Dosage (Strength)

    5mg, 20mg, 100mg, 180mg, 250mg

    Pregnancy

    Not Advised

    Brands

    Temodar, Temodal, Temcad

    Protein binding

    10–20%

    PubChem CID

    5394

    MedlinePlus

    a601250

    ChEBI

    72564

    ATC code

    L01AX03

    DrugBank

    DB00853

    KEGG

    D06067

    Routes of administration

    By mouth, intravenous

    Directions

    Take Temodar exactly as prescribed by your doctor.

    Ingredients

    The active ingredient is temozolomide.

    Interactions

    There are many potential drug-drug interactions, including:

    • Abrocitinib
    • Baricitinib
    • BCG Products
    • Cladribine
    • Coccidioides immitis Skin Test
    • COVID-19 Vaccine
    • Deferiprone
    • Dengue Tetravalent Vaccine
    • Denosumab
    • Dipyrone
    • Fexinidazole
    • Influenza Virus Vaccines
    • Leflunomide
    • Lenograstim
    • Lipegfilgrastim
    • Live Vaccines
    • Natalizumab
    • Palifermin
    • Pimecrolimus
    • Poliovirus Vaccine
    • Polymethylmethacrylate
    • Rabies Vaccine
    • Ropeginterferon Alfa-2b
    • Rubella- or Varicella-Containing Live Vaccines
    • Ruxolitinib
    • Sipuleucel-T
    • Tacrolimus
    • Talimogene Laherparepvec
    • Tertomotide
    • Tofacitinib
    • Typhoid Vaccine
    • Upadacitinib
    • Yellow Fever Vaccine

    Cautions

    Your oncology team should monitor the levels of your blood cells while taking this drug. 

    Do not take this drug if you are pregnant or intend to become pregnant.

    Tell your doctor if you have a history of liver problems.

    Side Effects

    The most common adverse reactions include:

    • Abdominal pain
    • Abnormal gait
    • Alopecia
    • Amnesia
    • Anaphylaxis
    • Anemia
    • Anorexia
    • Anxiety
    • Aplastic anemia
    • Arthralgia
    • Asthenia
    • Ataxia
    • Back pain
    • Blurred vision
    • Cholestasis
    • Confusion
    • Constipation
    • Cough
    • Decreased hemoglobin
    • Decreased neutrophils
    • Depression
    • Diabetes Insipidus
    • Diarrhea
    • Diplopia
    • Dizziness
    • Drowsiness
    • Dysgeusia
    • Dysphagia
    • Dyspnea
    • Erythema multiforme
    • Erythema of skin
    • Fatigue
    • Fever
    • Headache
    • Hematoma
    • Hemiparesis
    • Hepatitis
    • Hepatotoxicity
    • Hyperbilirubinemia
    • Hypercorticoidism
    • Hypersensitivity reaction
    • Increased liver enzymes
    • Infection
    • Injection site reaction
    • Insomnia
    • Interstitial pneumonitis
    • Irritation
    • Leukopenia
    • Lymphocytopenia
    • Mastalgia
    • Memory impairment
    • Myalgia
    • Myelodysplastic syndrome
    • Nausea
    • Pain
    • Pancytopenia
    • Paresis
    • Paresthesia
    • Peripheral edema
    • Petechiae
    • Pharyngitis
    • Pneumonia
    • Pneumonitis
    • Pruritus
    • Pruritus
    • Pulmonary alveolitis
    • Pulmonary fibrosis
    • Secondary acute myelocytic leukemia
    • Seizure
    • Sinusitis
    • Skin rash
    • Stevens-Johnson Syndrome
    • Stomatitis
    • Swelling
    • Thrombocytopenia
    • Toxic epidermal necrolysis
    • Upper respiratory tract infection
    • Urinary frequency
    • Urinary incontinence
    • Urinary tract infection
    • Viral infection
    • Visual disturbance
    • Vomiting
    • Warmth
    • Weight gain
    • Xeroderma

    References

    Temodar [package insert]. Whitehouse Station, NJ: Merck & Co., Inc.; 2016.


    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 10054

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