What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Tarceva (Erlotinib)
Prescription Required
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Product Details
Description
Tarceva is a prescription tyrosine kinase inhibitor (TKI) used for the treatment of certain types of cancers. It should only be prescribed by a provider specialized in the treatment of cancer.
Tarceva can treat certain types of non-small cell lung cancer (NSCLC) cancer and pancreatic cancer. It is commonly used along with other drugs.
Fact Table
Formula
C22H23N3O4
License
US FDA, EU EMA
Bioavailability
59%
Legal status
Rx-only
Chemical Name
Erlotinib
Elimination half-life
36.2 hrs
Dosage (Strength)
25mg
Pregnancy
Not Recommended
Brands
Tarceva
Protein binding
95%
PubChem CID
176870
MedlinePlus
a605008
ChEBI
114785
ATC code
L01EB02
DrugBank
DB00530
KEGG
D07907
Routes of administration
By mouth
Directions
Take Tarceva exactly as prescribed.
This drug should be taken on an empty stomach one hour before or two hours after meals.
Ingredients
The active ingredient in Tarceva is erlotinib.
Interactions
Tell your doctor and pharmacist if you are taking any of the following:
- Antacids
- Cannabis
- Ciprofloxacin
- Clofazimine
- CloZAPine
- CYP1A2 Inducers
- CYP3A4 Inducers
- Erdafitinib
- Fexinidazole
- FluvoxaMINE
- Fosphenytoin-Phenytoin
- Fusidic Acid
- Grapefruit Juice
- Histamine H2 Receptor Antagonists
- Hormonal Contraceptives
- Ivosidenib
- NiMODipine
- Proton Pump Inhibitors
- Rifabutin
- Rifapentine
- Selpercatinib
- Sirolimus
- St John's Wort
- Tacrolimus
- Tobacco
- Ubrogepant
- Warfarin
Cautions
There are many warnings and precautions associated with this drug. Speak with your pharmacist and doctor before starting this medication.
Side Effects
Common Tarceva side effects may include:
- Abdominal pain
- Acne vulgaris
- Acneiform eruption
- Alopecia
- Anemia
- Anorexia
- Anxiety
- Arthralgia
- Back pain
- Bullous dermatitis
- Chest pain
- Conjunctivitis
- Constipation
- Cough
- Decreased appetite
- Dermatitis
- Diarrhea
- Dizziness
- Dry eye syndrome
- Dyspepsia
- Dyspnea
- Epistaxis
- Erythema
- Erythematous rash
- Exfoliative dermatitis
- Fatigue
- Fever
- Folliculitis
- Headache
- Hepatic failure
- Hyperbilirubinemia
- Hypertrichosis
- Increased gamma-glutamyl transferase
- Increased serum alt
- Increased serum creatinine
- Increased susceptibility to infection
- Insomnia
- Interstitial pulmonary disease
- Leukopenia
- Lymphocytopenia
- Mucositis
- Muscle spasm
- Musculoskeletal chest pain
- Musculoskeletal pain
- Nail disease
- Nasopharyngitis
- Nausea
- Neurotoxicity
- Ostealgia
- Pain
- Palmar-plantar erythrodysesthesia
- Paresthesia
- Paronychia
- Peripheral edema
- Pneumonitis
- Pruritus
- Pulmonary embolism
- Pulmonary fibrosis
- Renal failure
- Respiratory tract infection
- Skin fissure
- Skin rash
- Stomatitis
- Taste disorder
- Thrombocytopenia
- Tinnitus
- Urinary tract infection
- Voice disorder
- Vomiting
- Weakness
- Weight loss
- Xeroderma
- Xerostomia
References
Tarceva [package insert]. Melville, NY: OSI Pharmaceuticals, Inc.; 2010.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 9484
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