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Supartz (Sodium Hyaluronate)

What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

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  • Product Details

    Description

    Supartz (sodium hyaluronate) is a medication that is given via an intra-articular injection to treat pain associated with osteoarthritis of the knee in patients who did not respond well to conservative, non-pharmacologic therapy and simple pain relievers like acetaminophen.

    Fact Table

    Formula

    (C14H21NO11)n (polymeric)

    License

    US FDA (1997)

    Bioavailability

    Localized effect; systemic absorption minimal

    Legal status

    Prescription only (Rx)

    Chemical Name

    Sodium hyaluronate

    Elimination half-life

    2–5 days (intra-articular space)

    Dosage (Strength)

    25 mg/mL in 2.5 mL prefilled syringe (62.5 mg total); given once weekly for 3–5 injections

    Pregnancy

    Consult a doctor (limited data available)

    Brands

    Supartz, Supartz FX

    Protein binding

    Not applicable

    PubChem CID

    24759 (monomeric unit)

    MedlinePlus

    a602021

    ChEBI

    CHEBI:132153

    ATC code

    M09AX01

    DrugBank

    DB08818

    KEGG

    D08551

    Routes of administration

    Intra-articular injection

    Directions

    Following strict aseptic techniques, a qualified healthcare provider will deliver Supartz via an intra-articular injection once a week for 5 total injections.

    It is recommended that you avoid strenuous activities or prolonged weight-bearing activities within 48 hours after receiving Supartz injection.

    Do not hesitate to reach out to your doctor with any questions or concerns.

    Ingredients

    The active ingredient in Supartz is sodium hyaluronate.

    Contraindications

    Supartz should not be administered to patients who are allergic to any of its ingredients or to patients with infections or skin diseases in the area of injection.

    Cautions

    • Before you start Supartz injections, talk to your doctor about:
      • All the medications you take, including prescription and over-the-counter medications
      • Your allergies
      • Your current health problems and past medical history
      • If you are pregnant or breastfeeding
    • Supartz contains the following warnings and precautions:
      • Disinfectants containing quaternary ammonium salts for preparing the skin should not be used with Supartz. Using them together can lead to precipitation of sodium hyaluronate.
      • It is unestablished if a single treatment cycle of less than 5 injections is effective.
      • It is unestablished if Supartz injection in joints other than the knee is safe and effective.
      • It is unestablished if using Supartz injection with other intra-articular injectables is safe and effective.
      • Caution should be used when administering Supartz to patients with allergies to avian proteins, feathers, and egg products.

    Side Effects

    Injection site reactions, injection site pain, joint pain, back pain, non-specific pain, headache, and joint issues are some Supartz side effects; however, other side effects may also occur.

    Contact your doctor right away if you have side effects that bother you or persist.

    Ask your doctor about whether Supartz shots are right for you.

    Reference

    1. Supartz. Tokyo, Japan: Seikagaku Corporation; 2001.


    Dr Savannah Muncy
    About Dr. Savannah Muncy (Page Author)


    Dr. Muncy (PharmD) studied science and education as an undergraduate before attending the Appalachian College of Pharmacy where she completed her PharmD in three years. She is currently using her pharmacy and healthcare expertise to write medical content for clients all around the world. She is focused on delivering the most current, accurate, and engaging information to healthcare professionals and patients. Read More....


    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 1937

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