What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Stribild (Elvitegravir, Cobicistat, Emtricitabine,Tenofovir Disoproxil Fumarate)
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Product Details
Description
Stribild is an all-in-one drug for the treatment of HIV infection in adults. This drug contains four different antiviral drugs that help to prevent the replication of HIV viral particles and help suppress chronic infection.
Fact Table
Formula
C94H120ClF2N16O27PS3
License
US FDA, EU EMA
Bioavailability
-
Legal status
Rx-only
Chemical Name
Elvitegravir,Cobicistat,Emtricitabine,Tenofovir
Elimination half-life
3.5 hours
Dosage (Strength)
150mg/150mg/200mg/300mg
Pregnancy
Consult Doctor
Brands
Stribild
Protein binding
97-98%
PubChem CID
44232548
MedlinePlus
a612035
ChEBI
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ATC code
J05AR09
DrugBank
DB09101
KEGG
D06677
Routes of administration
Buy Mouth
Directions
Take one tablet by mouth once daily with food.
Take this medication every day as directed. Missed doses can increase the risk of viral drug resistance.
Ingredients
The active ingredients in Stribild include: cobicistat, emtricitabine, elvitegravir, and tenofovir.
Interactions
Tell your doctor and pharmacist about all drugs you are taking before starting this medication, including:
- Acalabrutinib
- Adefovir
- Alfuzosin
- Alprazolam
- Aprepitant
- Astemizole
- Asunaprevir
- Asunaprevir
- Avanafil
- Avapritinib
- Barnidipine
- Bilastine
- Blonanserin
- Bosutinib
- Budesonide
- Carbamazepine
- Cisapride
- Cladribine
- Cobimetinib
- Conivaptan
- Dapoxetine
- Daridorexant
- Domperidone
- Doxorubicin
- Dronedarone
- Efavirenz
- Elagolix
- Elagolix, Estradiol, and Norethindrone
- Elbasvir and Grazoprevir
- Eletriptan
- Eplerenone
- Ergot Derivatives
- Everolimus
- Finerenone
- Flibanserin
- Fluticasone
- Fosamprenavir
- Fosaprepitant
- Fosphenytoin-Phenytoin
- Ibrutinib
- Infigratinib
- Isavuconazonium Sulfate
- Ivabradine
- Lasmiditan
- Lasmiditan
- Lefamulin
- Lemborexant
- Lercanidipine
- Levoketoconazole
- Lomitapide
- Lonafarnib
- Lovastatin
- Lumateperone
- Lurasidone
- Lurbinectedin
- Macitentan
- Midazolam
- Mitapivat
- Mobocertinib
- Naloxegol
- Neratinib
- Nevirapine
- Nimodipine
- Nisoldipine
- Oxcarbazepine
- Pacritinib
- Pazopanib
- Phenobarbital
- Pimozide
- Pralsetinib
- Primidone
- Radotinib
- Ranolazine
- Red Yeast Rice
- Regorafenib
- Revefenacin
- Rifampin
- Rifapentine
- Rimegepant
- Ritonavir
- Rivaroxaban
- Rupatadine
- Ruxolitinib
- Salmeterol
- Saquinavir
- Silodosin
- Simeprevir
- Simvastatin
- Sirolimus
- Sonidegib
- St John's Wort
- Suvorexant
- Tamsulosin
- Tazemetostat
- Tepotinib
- Terfenadine
- Ticagrelor
- Tipranavir
- Tolvaptan
- Topotecan
- Trabectedin
- Triazolam
- Ubrogepant
- Udenafil
- Vincristine
- Vinflunine
- Voclosporin
- Vorapaxar
- Voxilaprevir
Cautions
If your kidney function declines, you may need to stop taking Stribild.
Your doctor should monitor your liver and kidney function while taking this drug.
Ask your pharmacist and doctor for a full list of side effects before starting Stribild.
Side Effects
Common adverse reactions may include:
- Abnormal dreams
- Acute renal failure
- Bone fracture
- Diarrhea
- Dizziness
- Drowsiness
- Fatigue
- Flatulence
- Headache
- Hematuria
- Immune reconstitution syndrome
- Increased amylase
- Increased creatine phosphokinase
- Increased serum ALT
- Increased serum AST
- Increased serum cholesterol
- Increased serum creatinine
- Increased serum lipase
- Increased serum triglycerides
- Insomnia
- Nausea
- Proteinuria
- Renal failure
- Skin rash
References
Stribild. Foster City, CA: Gilead Sciences, Inc; 2017.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13627
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