What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Rukobia (Fostemsavir)
Prescription Required
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Product Details
Description
Rukobia is a prescription medication specifically indicated for the treatment of HIV-1. Your doctor may prescribe it alongside other antiretroviral drugs. Rukobia is typically reserved for patients who are “treatment experienced” and have tried other treatments.
Directions
The usual dosage is one tablet (600 mg) by mouth twice daily. Rukobia can be taken with or without food.
Ingredients
The active ingredient in Rukobia is fostemsavir.
Interactions
Common drug-drug interactions may include:
- Alpelisib
- Asunaprevir
- Atogepant
- Berotralstat
- Brincidofovir
- Cladribine
- Elagolix
- Elagolix, Estradiol, and Norethindrone
- Elbasvir and Grazoprevir
- Eluxadoline
- Ethinyl Estradiol-Containing Products
- Haloperidol
- Methadone
- Momelotinib
- PAZOPanib
- QT-prolonging Agents
- Revefenacin
- Statins
- St John's Wort
Cautions
Do not take Rukobia if you are allergic to any ingredients in the medication.
Tell your doctor and pharmacist about all medications you are taking before starting this drug because there are many potential side effects.
Tell your doctor if you have a history of cardiac problems and take any medications that prolong QTc (a measurement of heart rhythm).
Tell your doctor if you have a history of hepatitis B or hepatitis C infection.
Side Effects
Common adverse reactions to Rukobia typically include
- Abdominal pain
- Decreased hemoglobin (grades 3/4)
- Decreased neutrophils (grades 3/4)
- Dermatologic: Pruritus, skin rash
- Diarrhea
- Dizziness
- Drowsiness
- Dysgeusia
- Dyspepsia
- Fatigue
- Headache
- Hypercholesterolemia (grade 3)
- Hyperglycemia (grades 3/4)
- Immune reconstitution syndrome
- Increased direct serum bilirubin (grade 3)
- Increased LDL cholesterol (grades 3/4)
- Increased serum alanine aminotransferase (grades 3/4)
- Increased serum aspartate aminotransferase (grades 3/4)
- Increased serum bilirubin (grades 3/4)
- Increased serum creatine kinase (grades 3/4)
- Increased serum creatinine (grades 3/4)
- Increased serum lipase (grades 3/4)
- Increased serum triglycerides (grades 3/4)
- Increased uric acid (grades 3/4)
- Leukocyte disorder (grades 3/4)
- Myalgia
- Nausea
- Peripheral Neuropathy
- Peripheral Sensory Neuropathy
- Prolonged QT interval
- Sleep Disturbance
- Vomiting
References
Rubokia [package insert]. Research Triangle Park, NC: ViiV Healthcare; July 2020.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 14408
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