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Riximyo (Rituximab)

What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

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  • Product Details

    Description

    Riximyo (rituximab) uses: Riximyo is an intravenous medication given to adults to treat non-Hodgkin's lymphoma, chronic lymphocytic leukemia, rheumatoid arthritis, granulomatosis with polyangiitis and microscopic polyangiitis, and pemphigus vulgaris.

    Fact Table

    Formula

    C6416H9874N1688O1987S44

    License

    US FDA, EMA

    Bioavailability

    N/A (Intravenous administration)

    Legal status

    Prescription only

    Chemical Name

    Rituximab

    Elimination half-life

    18-22 days

    Dosage (Strength)

    100 mg/10 mL, 500 mg/50 mL

    Pregnancy

    Consult a doctor

    Brands

    Rituxan, MabThera, Rixathon, Riximyo, Truxima

    Protein binding

    N/A

    PubChem CID

    50958573

    MedlinePlus

    a607038

    ChEBI

    63638

    ATC code

    L01XC02

    DrugBank

    DB00073

    KEGG

    D02993

    Routes of administration

    Intravenous

    Directions

    Your healthcare provider will decide on the right treatment plan for you. A healthcare professional will administer Riximyo intravenous infusion. Your healthcare provider may also give you medications prior to your infusion to help manage side effects.

    Talk to your healthcare provider if you have any questions or concerns.

    Ingredients

    The active ingredient in Riximyo is rituximab.

    Contraindications

    Patients with any of the following should not receive Riximyo infusion:

    • An allergy to any of the ingredients in Riximyo
    • Active infections that are severe
    • A weak immune system
    • Severe heart failure or heart disease (when used for rheumatoid arthritis, granulomatosis with polyangiitis, microscopic polyangiitis, and pemphigus vulgaris)

    Cautions

    • Before you begin Riximyo treatment, talk to your healthcare provider about:
      • All the prescription and over-the-counter medications you take
      • Your allergies
      • Your current health problems and past medical history
      • Your pregnancy or breastfeeding status
    • Progressive multifocal leukoencephalopathy can rarely occur.
    • Infusion-related reactions that may become severe or fatal can occur.
    • Hypersensitivity reactions, including anaphylaxis, can occur.
    • Heart problems can occur.
    • Abnormal blood cell counts can occur.
    • Infections can occur, including hepatitis B reactivation.
    • Live vaccines are not recommended while being treated with Riximyo.

    Side Effects

    Infections, abnormal blood cell counts, infusion-related reactions, nausea, itching, rash, hair loss, fever, chills, weakness, and headache are common side effects associated with Riximyo. However, other side effects may also occur. Immediately inform your healthcare provider of side effects that bother you or won’t go away.

    Ask your healthcare provider about Riximyo.

    Reference:

    Riximyo. European Medicines Agency; 2022.



    Dr Savannah Muncy
    About Dr. Savannah Muncy (Page Author)


    Dr. Muncy (PharmD) studied science and education as an undergraduate before attending the Appalachian College of Pharmacy where she completed her PharmD in three years. She is currently using her pharmacy and healthcare expertise to write medical content for clients all around the world. She is focused on delivering the most current, accurate, and engaging information to healthcare professionals and patients. Read More....


    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 14444

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