What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Restasis (Cyclosporine) Opthalmic Emulsion
Generic Equivalent - Restasis (Cyclosporine) Opthalmic Emulsion
Prescription Required
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Product Details
Description
RESTASIS (Cyclosporine) is an ophthalmic medication prescribed to treat certain conditions of the eye. RESTASIS (cyclosporine) treats keratoconjunctivitis sicca, which is when the eye produces fewer tears because of inflammation. During inflammation, the eye is swollen, red, and sometimes itchy and irritated. Inflammation may slow or stop tear production.
RESTASIS increases the production of tears, relieving dry eyes
RESTASIS contains an immunosuppressive agent, cyclosporine, that reduces inflammation. The exact mechanism is not well understood.
Fact Table
Formula
C62H111N11O12
License
EU EMA
Bioavailability
Varies
Legal status
RX Only
Chemical Name
Cyclosporine
Elimination half-life
Variable (about 24 hours)
Dosage (Strength)
0.4ml each (30 vials, 60 vials), 0.05% (5.5ml)
Pregnancy
Consult a doctor
Brands
Restasis
Protein binding
Greater than 95%
PubChem CID
5284373
MedlinePlus
a601207
ChEBI
4031
ATC code
L04AD01
DrugBank
DB00091
KEGG
D00184
Routes of administration
By mouth
Directions
Instill one drop of RESTASIS twice daily into each eye.
Separate the administration of RESTASIS by at least 15 minutes from other ophthalmic products.
The vial should be gently inverted several times until the solution becomes a uniform, white, and opaque.
Ingredients
The active ingredient of RESTASIS is cyclosporine 0.05%.
The inactive ingredients are carbomer copolymer type A, castor oil, polysorbate 80, purified water, and sodium hydroxide.
Cautions
Do not touch the tip of RESTASIS to the eye or other surfaces. Doing so may contaminate the product and lead to infections of the eye.
Remove contact lenses before applying RESTASIS. Lenses should be reinserted at least 15 minutes after applying RESTASIS.
RESTASIS has not shown to increase tear production in patients taking topical anti-inflammatory drugs or those wearing punctal pugs.
Side Effects
The most common adverse effects of RESTASIS include:
- Blepharitis
- Blurred vision
- Burning sensation of eyes
- Conjunctival hyperemia
- Epiphora
- Eye discharge
- Eye irritation
- Eye pain
- Eye pruritus
- Feeling of a "foreign body" in the eye
- Headache
- Stinging of the eyes
- Urinary tract infection
- Visual disturbance
RESTASIS eye drops can be bought online with a valid prescription from a doctor.
References
- Restasis [package insert]. Irvine, CA: Allergan, 2012.
Frequently Asked Questions about Restasis (Cyclosporine Ophthalmic Emulsion)
What does Restasis do to the eye?
Restasis (Cyclosporine Ophthalmic Emulsion) is used to treat chronic dry eye syndrome. It works by reducing inflammation in the eyes and increasing tear production. This helps alleviate dryness and discomfort.
When should you not use Restasis?
Restasis should not be used if you are allergic to any of its ingredients. Additionally, it should not be used while wearing contact lenses. If you wear contacts, remove them before using Restasis, and you can reinsert them after 15 minutes.
How long can you stay on Restasis?
In general, it is advised to use Restasis for a minimum of 6 months. However, the duration of Restasis use varies for every individual. Consult your eye doctor for personalized advice. Some individuals may use it long-term, while others may use it for shorter periods.
Is it OK to use 2 drops of Restasis?
The usual dosage for adults is one drop in each eye twice daily (approximately every 12 hours). Using more than the recommended amount may not provide additional benefits and could increase the risk of side effects. Always consult your doctor.
What happens when you stop using Restasis?
When you stop using Restasis, your eyes may return to their previous dry state. It’s essential to follow your doctor’s instructions and continue using it as recommended to maintain its effectiveness.
Why does Restasis burn?
Some people experience a mild burning or stinging sensation when using Restasis. This is a common side effect due to the medication’s action on the eyes. It usually diminishes over time.
Do Restasis side effects go away?
Side effects of Restasis may include burning, redness, and temporary blurred vision. These effects often improve with continued use. If they persist or worsen, consult your doctor.
Does Restasis need to be refrigerated?
No, Restasis does not need refrigeration. Store it at room temperature (between 59°F and 77°F or 15°C and 25°C).
Is Restasis a steroid eye drop?
No, Restasis is not a steroid eye drop. It contains cyclosporine, which works differently to reduce inflammation and increase tear production.
Can I use Restasis with pink eye?
It’s best to consult your eye doctor before using Restasis if you have pink eye (conjunctivitis). They can advise you based on your specific condition.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 9592
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