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Remsima (Infliximab)

What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

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  • Product Details

    Description

    Remsima (infliximab) is a medication given intravenously to treat rheumatoid arthritis, Crohn's disease, ulcerative colitis, ankylosing spondylitis, psoriatic arthritis, and psoriasis.

    Fact Table

    Formula

    C6428H9912N1694O1987S46

    License

    US FDA, EMA

    Bioavailability

    N/A (Intravenous administration)

    Legal status

    Prescription only

    Chemical Name

    Infliximab

    Elimination half-life

    7.7-12 days

    Dosage (Strength)

    100 mg/vial

    Pregnancy

    Consult a doctor

    Brands

    Remicade, Inflectra, Remsima, Renflexis

    Protein binding

    N/A

    PubChem CID

    16129619

    MedlinePlus

    a604005

    ChEBI

    63641

    ATC code

    L04AB02

    DrugBank

    DB00065

    KEGG

    D02596

    Routes of administration

    Intravenous

    Directions

    Your healthcare provider will determine an appropriate treatment regimen for you and will administer Remsima intravenous infusion (given via a vein).

    If you have any questions or concerns, talk to your healthcare provider.

    Ingredients

    The active ingredient in Remsima is infliximab. Inactive ingredients include sucrose, polysorbate 80, sodium dihydrogen phosphate monohydrate, and disodium phosphate dihydrate.

    Contraindications

    Patients with any of the following should not receive Remsima:

    • An allergy to any of the ingredients in Remsima
    • Tuberculosis or other serious infection, including sepsis, abscesses, and opportunistic infections
    • Moderate or severe heart failure

    Cautions

    • Before you begin treatment with Remsima, talk to your healthcare provider about:
      • All the prescription and over-the-counter medications you take
      • Your allergies
      • Your current health problems and past medical history
      • Your pregnancy or breastfeeding status
    • Infusion reactions and hypersensitivity, including anaphylactic shock, can occur. Treatment should be started right away in cases of these events.
    • Infections can occur, including invasive fungal infections, hepatitis B reactivation, and active tuberculosis. Patients should be evaluated for infections prior to starting Remsima therapy. Remsima may need to be stopped if a patient develops a new infection.
    • Liver inflammation can occur.
    • Patients receiving Remsima should avoid getting live vaccinations.
    • Worsening or new central nervous system demyelinating disorders can occur.
    • Cancers such as lymphoma can occur.
    • Caution should be used in patients with heart failure.
    • Abnormal blood cell counts can occur.

    Side Effects

    Infections, abnormal blood cell counts, allergic reactions, depression, trouble sleeping, headache, dizziness, rapid heart rate, blood pressure problems, stomach pain, nausea, liver problems, joint pain, muscle pain, and back pain are common Remsima side effects. However, other side effects may also occur. Immediately inform your healthcare provider of side effects that bother you or won’t go away.

    Ask your healthcare provider about Remsima injection.

    Reference:

    Remsima. European Medicines Agency; 2018.



    Dr Savannah Muncy
    About Dr. Savannah Muncy (Page Author)


    Dr. Muncy (PharmD) studied science and education as an undergraduate before attending the Appalachian College of Pharmacy where she completed her PharmD in three years. She is currently using her pharmacy and healthcare expertise to write medical content for clients all around the world. She is focused on delivering the most current, accurate, and engaging information to healthcare professionals and patients. Read More....


    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 14443

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