Description
Razadyne contains the active ingredient galantamine, which is used in people with Alzheimer’s disease (AD). Patients with AD have a variety of symptoms that impact their life, including dementia. Razadyne is improved to treat dementia symptoms, including mental decline, inability to recognize common things, mood swings, hallucinations, and memory loss.
Fact Table |
Formula |
C17H21NO3 |
License |
US FDA |
Bioavailability |
80–100% |
Legal status |
Rx-only |
Chemical Name |
Galantamine |
Elimination half-life |
7 hour |
Dosage (Strength) |
4mg, 8mg |
Pregnancy |
Consult Doctor |
Brands |
Razadyne |
Protein binding |
18% |
PubChem CID |
9651 |
MedlinePlus |
a699058 |
ChEBI |
42944 |
ATC code |
N06DA04 |
DrugBank |
DB00674 |
KEGG |
D04292 |
Routes of administration |
By mouth |
Directions
Take Razadyne exactly as prescribed by the healthcare provider.
The usual starting dose is Razadyne 4 mg by mouth twice daily. After four weeks, your dose may be increased to Razadyne 8 mg twice daily. The dosage can again be increased after four weeks to a maximum of 12 mg twice daily.
Ingredients
The active ingredient in Razadyne is galantamine.
Interactions
Razadyne has a high potential for drug-drug interactions, including:
- Abiraterone
- Anticholinergic agents
- Antipsychotic agents
- Atazanavir
- Beta-blockers
- Bupropion
- Ceritinib
- Ceritinib
- Cinacalcet
- Clarithromycin
- Cobicistat and cobicistat-containing coformulations
- Corticosteroids
- Dacomitinib
- Darifenacin
- Darunavir
- Darunavir
- Duloxetine
- Fedratinib
- Fluoxetine
- Givosiran
- Idelalisib
- Indinavir
- Itraconazole
- Ketoconazole
- Lonafarnib
- Lopinavir
- Lorcaserin
- Mifepristone
- Mirabegron
- Nefazodone
- Nelfinavir
- Ombitasvir-paritaprevir-ritonavir
- Ombitasvir-paritaprevir-ritonavir plus dasabuvir
- Paroxetine
- Posaconazole
- Quinidine
- Ritonavir and ritonavir-containing coformulations
- Rolapitant
- Saquinavir
- Succinylcholine
- Telithromycin
- Terbinafine (systemic)
- Thioridazine
- Tipranavir
- Tucatinib
- Voriconazole
Cautions
If you have trouble breathing while taking Razadyne, stop taking it and call your healthcare provider.
Stop taking Razadyne right away if you develop a skin rash.
Your doctor should perform tests for heart diseases before starting Razadyne.
Side Effects
The most common side effects may include:
- Abdominal distress
- Abdominal pain
- Bradycardia
- Decreased appetite
- Depression
- Diarrhea
- Dizziness
- Drowsiness
- Dyspepsia
- Falling
- Fatigue
- Headache
- Laceration
- Lethargy
- Malaise
- Muscle spasm
- Nausea
- Syncope
- Tremor
- Vomiting
- Weight loss
References
- Razadyne [package insert]. Titusville, NJ: Janssen Pharmaceuticals; 2015.
Frequently Asked Questions about Razadyne
What is Razadyne, and what is it used for?
Razadyne, also known as Galantamine, is a medication primarily used to treat mild to moderate Alzheimer's disease. It is prescribed to help improve cognitive function and memory in individuals with this condition.
How does Razadyne work?
Razadyne works by increasing the levels of certain neurotransmitters, such as acetylcholine, in the brain. This helps to improve communication between nerve cells and can temporarily alleviate some of the symptoms of Alzheimer's disease.
Is Razadyne a cure for Alzheimer's disease?
No, Razadyne is not a cure for Alzheimer's disease. It is a symptomatic treatment that may temporarily improve cognitive function and quality of life in individuals with mild to moderate Alzheimer's disease.
What are the common side effects of Razadyne?
Common side effects of Razadyne may include nausea, vomiting, diarrhea, loss of appetite, dizziness, and headache. These side effects are generally mild and may improve with time or dosage adjustments.
Can Razadyne be used in severe Alzheimer's disease cases?
Razadyne is typically prescribed for mild to moderate Alzheimer's disease. It may not be as effective in severe cases, and the decision to use it in severe cases should be made by a healthcare professional.
Is Razadyne safe for long-term use?
Razadyne can be used for long-term treatment, but its safety and effectiveness should be monitored regularly by a healthcare provider. They may adjust the dosage or recommend discontinuing the medication if necessary.
How should Razadyne be taken?
Razadyne is usually taken by mouth with food to minimize stomach upset. The dosage and administration instructions should be followed as prescribed by your healthcare provider.
Can Razadyne be used in combination with non-drug therapies for Alzheimer's?
Yes, Razadyne can be used alongside non-drug therapies like cognitive stimulation, physical exercise, and a healthy diet. Combining medication with these therapies may provide the best results in managing Alzheimer's disease.
Is Razadyne suitable for all individuals with Alzheimer's disease?
Razadyne may not be suitable for everyone with Alzheimer's disease. It should be prescribed and monitored by a healthcare provider who can assess its appropriateness for each individual's unique situation.
Can Razadyne prevent the progression of Alzheimer's disease?
Razadyne is not a disease-modifying medication, so it does not prevent or slow down the progression of Alzheimer's disease. It primarily helps manage the symptoms of the condition.
About Dr. Conor Sheehy (Page Author)
Dr. Sheehy (BSc Molecular Biology, PharmD) works a clinical pharmacist specializing in cardiology, oncology, and ambulatory care. He’s a board-certified pharmacotherapy specialist (BCPS), and his experience working one-on-one with patients to fine tune their medication and therapy plans for optimal results makes him a valuable subject matter expert for our pharmacy. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 9376