Description
Quilonum SR is a mood-stabilizing agent used to treat bipolar I disorder, a mental health condition characterized by episodes of depression and mania. It can be used in patients 12 years or older.
Quilonum SR works as a mood stabilizer, but its mechanism of action is unknown.
Fact Table |
Formula |
Li2CO3 |
License |
US DailyMed |
Bioavailability |
Close to 100% |
Legal status |
Rx-Only |
Chemical Name |
Lithium carbonate |
Elimination half-life |
1.0-2.0 hours |
Dosage (Strength) |
450mg |
Pregnancy |
Consult Doctor |
Brands |
Quilonum SR |
Protein binding |
Not significantly protein bound |
PubChem CID |
11125 |
MedlinePlus |
a681039 |
ChEBI |
6504 |
ATC code |
N05AN01 |
DrugBank |
DB14509 |
KEGG |
D00801 |
Routes of administration |
By mouth |
Directions
The usual dosage of Quilonum SR is 450 mg twice daily. Do not break, chew, or crush the tablets.
Ingredients
The active ingredient in Quilonum SR is lithium carbonate.
Interactions
Common interactions include:
- Almotriptan
- Alosetron
- Amphetamines
- Angiotensin II Receptor Blockers
- Angiotensin-Converting Enzyme Inhibitors
- Antipsychotic Agents
- BusPIRone
- Calcitonin
- Calcium Channel Blockers (Nondihydropyridine)
- Calcium Polystyrene Sulfonate
- CarBAMazepine
- Carbonic Anhydrase Inhibitors
- Cyclobenzaprine
- Dapoxetine
- Desmopressin
- Dexmethylphenidate-Methylphenidate
- Dextromethorphan
- Lithium
- Nonsteroidal Anti-Inflammatory Agents
- Opioid Agonists
- Potassium Iodide
- QT-prolonging Agents
Cautions
Before taking Quilonum SR, inform your doctor if you have a history of kidney disease, heart disease, thyroid problems, or epilepsy, as these conditions may affect the dosage or frequency of your medication.
Your healthcare provider will monitor lithium levels to ensure you get the correct dosage.
Ask your pharmacist or doctor for a full list of precautions.
Side Effects
Common adverse reactions include:
- Abdominal pain
- Abnormal electroencephalogram
- Abnormal gait
- Acne vulgaris
- Albuminuria
- Alopecia
- Angioedema
- Anorexia
- Arthralgia
- Bradyphrenia
- Blurred vision
- Cardiac arrhythmia
- Chest tightness
- Circulatory shock
- Cold extremities
- Coma
- Confusion
- Decreased creatinine clearance
- Decreased mental acuity
- Dental caries
- Dermatitis
- Disorientation
- Dizziness
- Dry or thinning hair
- Dysgeusia
- Dyspepsia
- Edema
- Euthyroid goiter
- Exacerbation of acne
- Exacerbation of psoriasis
- Exophthalmos
- Extrapyramidal reaction
- Fatigue
- Fecal incontinence
- Fever
- Flatulence
- Folliculitis
- Glomerulopathy
- Glycosuria
- Hallucination
- Headache
- Hyperactive behavior
- Hyperactive deep tendon reflex
- Hypercalcemia
- Hyperglycemia
- Hypermagnesemia
- Hyperparathyroidism
- Hyperthyroidism
- Hypertonia
- Hypotension
- Hyponatremia
- Impotence
- Iodism
- Joint swelling
- Lethargy
- Local pain
- Local skin discoloration
- Localized edema
- Memory impairment
- Myasthenia
- Myxedema
- Nephron atrophy
- Nephrotic syndrome
- Nystagmus disorder
- Oliguria
- Peripheral vascular disease
- Polyarthralgia
- Pruritus
- Prolonged QT interval
- Psychomotor impairment
- Raynaud’s syndrome
- Renal concentrating defect
- Restlessness
- Salivary gland disease
- Seizure
- Sexual disorder
- Sialorrhea
- Sinus node dysfunction
- Skin rash
- Slurred speech
- Stupor
- Syncope
- Tic disorder
- Tinnitus
- Transient scotoma
- Tremor
- Urinary incontinence
- Ventricular tachyarrhythmia
- Vertigo
- Vomiting
- Weight loss
- Xeroderma
- Xerostomia
References
- Quilonum SR [patient leaflet]. St Leonards NSW 2065 Australia: Aspen Pharmacare: 2018.
About Dr. Conor Sheehy (Page Author)
Dr. Sheehy (BSc Molecular Biology, PharmD) works a clinical pharmacist specializing in cardiology, oncology, and ambulatory care. He’s a board-certified pharmacotherapy specialist (BCPS), and his experience working one-on-one with patients to fine tune their medication and therapy plans for optimal results makes him a valuable subject matter expert for our pharmacy. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 13866