What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Proloprim (Trimethoprim)
We don't have this brand product yet!
Sign up to get exclusive coupon discounts and be the first to be notified when we have this product available.
Prescription Required
-
Related Products & Conditions
-
Product Details
Description
Proloprim (trimethoprim) is a prescription medication used to treat certain bacterial infections.
Proloprim (trimethoprim) is available in 100 mg oral tablets.
The brand product is no longer available in the US; however, generic alternatives may be available.
Fact Table
Formula
C14H18N4O3
License
US FDA
Bioavailability
90–100%
Legal status
Prescription only (Rx)
Chemical Name
Trimethoprim
Elimination half-life
8–10 hours
Dosage (Strength)
100 mg and 200 mg tablets
Pregnancy
Category C — caution advised; folate antagonist
Brands
Proloprim, Trimpex (discontinued), generic trimethoprim
Protein binding
~44%
PubChem CID
5578
MedlinePlus
a684025
ChEBI
45948
ATC code
J01EA01
DrugBank
DB00440
KEGG
D00145
Routes of administration
Oral
Directions
Take Proloprim (trimethoprim) medication exactly as prescribed by your doctor. Your doctor will tell you how much medication you should take and how long you should receive treatment based on the condition being treated and other factors, including kidney function.
Refer to the medication guide that comes with your prescription for additional instructions for use.
Call your doctor or pharmacist if you have any questions or concerns.
Ingredients
The active ingredient in Proloprim is trimethoprim.
Contraindications
Do not take Proloprim (trimethoprim) if you are allergic to trimethoprim or if you have diagnosed megaloblastic anemia due to a deficiency in folate.
Cautions
- Before you begin treatment with Proloprim (trimethoprim), talk to your doctor about:
- All the medications you take, including prescription and over-the-counter medications, vitamins, supplements, and herbals
- Any allergies you may have
- Your current health problems and past medical history
- If you are pregnant or breastfeeding
- Allergic reactions have occurred with the use of trimethoprim.
- Trimethoprim has been shown to interfere with blood cell production, especially when taking high doses and/or for a long period of time. Sore throat, fever, pale appearance, or purple spots on the skin may be signs of serious blood disorders.
- Caution should be exercised in patients at risk for folate deficiency and in patients with kidney or liver impairment.
- High potassium levels in the blood can occur, particularly with high doses, kidney impairment, or when taking Proloprim (trimethoprim) with other medications that can increase potassium levels.
- Long-term use of Proloprim (trimethoprim) may result in fungal or bacterial superinfection; this can occur more than 2 months after treatment with the medication.
- Some dosage forms of trimethoprim may contain benzyl alcohol and derivatives, and therefore, should not be administered to newborns.
Side Effects
Rash, itching, and other skin conditions; hypersensitivity reactions, including anaphylaxis; nausea and/or vomiting; abnormal blood cell counts; high potassium levels in the blood; low sodium levels in the blood; and fever are possible side effects of Proloprim (trimethoprim); however, other side effects may also occur.
Notify your doctor right away if you have side effects that bother you or won’t go away.
Ask your doctor about Proloprim (trimethoprim).
Reference
- Trimethoprim. Medscape.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 1747
-
Product Reviews