What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Prestalia (Perindopril and Amlodipine)
Also Known as Viacoram
Generic Equivalent - Prestalia (Perindopril and Amlodipine)
Prescription Required
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Product Details
Description
Prestalia is a combination medication (perindopril and amlodipine) that is prescribed to treat high blood pressure.
Prestalia is available in oral tablets containing either of the following:
- 3.5 mg perindopril/2.5 mg amlodipine
- 7 mg perindopril/5 mg amlodipine
- 14 mg perindopril/10 mg amlodipine
Directions
Take Perstalia as prescribed by your doctor. If you have any questions or concerns, talk to your doctor or pharmacist.
Your doctor will determine an appropriate dose for you based on your medical conditions and blood pressure goals. Patients are generally started on 3.5 mg/2.5 mg by mouth once daily with or without food. Your doctor may gradually adjust your dose based on how well you respond to and tolerate the medication.
The maximum daily dose is 14 mg/10 mg.
Ingredients
Perindopril arginine, an angiotensin-converting enzyme (ACE) inhibitor, and amlodipine, a calcium channel blocker, are the active ingredients in Prestalia.
Contraindications
Patients should not take Prestalia if they have ever had angioedema (swelling) with previous ACE inhibitor use.
Patients should not take Prestalia with neprilysin inhibitors such as sacubitril. Do not take Prestalia within 36 hours of switching to or from neprilysin inhibitors. Ask your doctor if you are unsure whether you take neprilysin inhibitors.
Diabetic patients or patients with kidney problems should not take Prestalia with aliskiren.
Cautions
- Prestalia contains the following FDA Boxed Warning:
- Stop Prestalia as soon as pregnancy is detected, as the medication can cause harm or death to an unborn baby.
- Before you start taking Prestalia, tell your doctor:
- About all the prescription and over-the-counter medications you take
- About your allergies
- About your current health conditions and past medical history
- If you are pregnant or breastfeeding
- Worsening chest pain or a heart attack can occur at initiation of Prestalia or with dosage increases, especially in patients with severe obstructive coronary artery disease.
- High potassium levels in the blood can occur. Potassium levels should be monitored.
- Taking Prestalia with mTOR inhibitors such as temsirolimus can increase the risk of angioedema.
- A persistent cough can occur due to the ACE inhibitor component of Prestalia. The cough typically goes away after stopping the medication.
- Rare liver problems that can result in death may occur.
- Low blood pressure can occur. Blood pressure should be regularly monitored.
- Kidney problems can occur. Kidney function should be periodically monitored.
- Anaphylactoid reactions such as angioedema can occur. Seek emergency care right away if you experience abdominal pain or swelling of the face, arms, legs, lips, tongue, or throat.
Side Effects
Swelling, cough, headache, and dizziness are possible Prestalia side effects. However, these are not the only side effects that can occur. Call your doctor right away if you have side effects that bother you or won’t go away.
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Reference
Prestalia. Medscape.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13900
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