What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Feldene (Piroxicam)
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Product Details
Description
Feldene is a medication prescribed for the treatment of pain in osteoarthritis or rheumatoid arthritis. Feldene works by inhibiting cyclooxygenase-1 and 2.
Fact Table
Formula
C15H13N3O4S
License
US FDA
Bioavailability
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Legal status
Rx-only
Chemical Name
Piroxicam
Elimination half-life
50 hours
Dosage (Strength)
10mg, 20mg
Pregnancy
Consult Doctor
Brands
Feldene
Protein binding
99%
PubChem CID
54676228
MedlinePlus
a684045
ChEBI
8249
ATC code
M01AC01
DrugBank
DB00554
KEGG
D00127
Routes of administration
By mouth
Directions
The usual dosage is 20 mg by mouth once daily. Feldene should be taken with food to minimize stomach upset.
Ingredients
The active ingredient is piroxicam.
Interactions
The most common drug-drug interactions are:
- Abrocitinib
- Acemetacin
- Aminolevulinic Acid
- Apixaban
- Bemiparin
- CycloSPORINE
- Dabigatran Etexilate
- Edoxaban
- Enoxaparin
- Heparin
- Ketorolac
- Lithium
- Loop Diuretics
- Macimorelin
- Methotrexate
- Mifamurtide
- Nirmatrelvir
- Nonsteroidal Anti-Inflammatory Agents
- Phenylbutazone
- PRALAtrexate
- Rivaroxaban
- Salicylates
- Selective Serotonin Reuptake Inhibitors
- Sincalide
- Sodium Phosphates
- Tenofovir Products
- Tenoxicam
- Urokinase
- Vitamin K Antagonists
Cautions
Tell your doctor if you have a history of heart or kidney problems before taking this medication.
Feldene may cause drowsiness or dizziness in some patients.
Ask your doctor and pharmacist for a full list of precautions that might apply to you.
Side Effects
Common adverse reactions may include:
- Abdominal pain
- Abnormal dreams
- Acute myocardial infarction
- Agranulocytosis
- Akathisia
- Alopecia
- Anaphylaxis
- Anemia
- Angioedema
- Anorexia
- Anxiety
- Aplastic anemia
- Asthenia
- Asthma
- Auditory impairment
- Blurred vision
- Bruise
- Cardiac arrhythmia
- Cardiac failure
- Cerebrovascular accident
- Change in appetite
- Colic
- Coma
- Confusion
- Conjunctivitis
- Constipation
- Coronary thrombosis
- Cystitis
- Depression
- Desquamation
- Diaphoresis
- Diarrhea
- Dizziness
- Drowsiness
- Dyspepsia
- Dyspnea
- Dysuria
- Ecchymoses
- Edema
- Eosinophilia
- Epistaxis
- Eructation
- Erythema multiforme
- Erythema of skin
- Esophagitis
- Exacerbation of angina pectoris
- Exfoliative dermatitis
- Female infertility
- Fever
- Flatulence
- Fluid Retention
- Flu-like symptoms
- Gastritis
- Gastrointestinal hemorrhage
- Gastrointestinal inflammation
- Gastrointestinal perforation
- Gastrointestinal ulcer
- Glomerulonephritis
- Glossitis
- Hallucination
- Headache
- Heartburn
- Hematemesis
- Hematuria
- Hemolytic anemia
- Hepatic failure
- Hepatitis
- Hepatotoxicity
- Hyperglycemia
- Hyperkalemia
- Hypertension
- Hypoglycemia
- Hypotension
- Increased liver enzymes
- Infection
- Insomnia
- Interstitial nephritis
- Jaundice
- Leukopenia
- Lymphadenopathy
- Malaise
- Melena
- Meningitis
- Mood changes
- Nausea
- Nephrotic syndrome
- Nervousness
- Oliguria
- Onycholysis
- Palpitations
- Pancreatitis
- Pancytopenia
- Paresthesia
- Petechial rash
- Pneumonia
- Polyuria
- Positive ANA titer
- Prolonged bleeding time
- Proteinuria
- Pruritus
- Purpuric disease
- RectalhHemorrhage
- Renal failure syndrome
- Renal function abnormality
- Respiratory depression
- Seizure
- Sepsis
- Serum sickness
- Skin photosensitivity
- Skin Rash
- Stevens-Johnson syndrome
- Stomatitis
- Swelling of eye
- Syncope
- Tachycardia
- Thrombocytopenia
- Tinnitus
- Toxic epidermal necrolysis
- Tremor
- Urticaria
- Vasculitis
- Vertigo
- Vesiculobullous reaction
- Vomiting
- Weight Changes
- Xerostomia
References
- Feldene [package insert]. New York, NY: Pfizer Inc; 2015.
Frequently Asked Questions about Feldene (Piroxicam)
What is Feldene used for?
Feldene (Piroxicam) is a nonsteroidal anti-inflammatory drug (NSAID) used to treat symptoms of arthritis including joint pain, swelling, and stiffness.
How should Feldene be taken?
Feldene is typically taken orally once daily, and it's available in capsule form. The usual dosage for relief of rheumatoid arthritis and osteoarthritis is 20 mg given orally once per day.
What are the available strengths of Feldene?
Feldene is available as 10 mg and 20 mg capsules.
What are the side effects of Feldene?
Common side effects include diarrhea, nausea, vomiting, and rash. Serious side effects may include severe stomach pain, unusual bleeding or bruising, and allergic reactions.
How long does it take for Feldene to work?
Although the therapeutic effects of Feldene are evident early in treatment, steady-state blood levels are not reached for 7 to 12 days due to its long half-life.
Does Feldene cure arthritis?
No, Feldene does not cure arthritis but helps in relieving symptoms as long as it is being taken.
Is Feldene the same as Piroxicam?
Yes, Feldene is the brand name for the drug Piroxicam.
What group of drugs does Feldene belong to?
Feldene belongs to a group of medications known as NSAIDs, which work by decreasing pain and inflammation.
Are there any other forms of Feldene besides capsules?
While the commonly used form is the oral capsule, there is also a gel form known as Piroxicam gel for topical use, primarily used for pain relief due to strains, sprains, backache, or arthritis.
Are there any special precautions to follow while taking Feldene?
Patients are advised to avoid the use of Feldene in cases of recent heart attacks unless the benefits are expected to outweigh the risks. It's also crucial to monitor for signs of cardiac ischemia if Feldene is used in such circumstances.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 1945
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