What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Peridex (Chlorhexidine) 0.12% oral rinse
Prescription Required
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Product Details
Description
Peridex is an oral rinse that is prescribed to treat gingivitis.
Peridex is available as a liquid in the following sizes:
- 15 mL amber plastic bottle
- 118 mL amber plastic bottle
- 473 mL amber plastic bottle
- 1,893 mL white plastic bottle
The Peridex generic is chlorhexidine gluconate 0.12%.
Fact Table
Formula
C22H30Cl2N10 (Chlorhexidine Gluconate)
License
US FDA
Bioavailability
Poorly absorbed through oral mucosa
Legal status
Prescription only (Rx)
Chemical Name
1,1'-Hexamethylene-bis(5-(p-chlorophenyl)biguanide) di-D-gluconate
Elimination half-life
10 hours (plasma)
Dosage (Strength)
0.12% solution
Pregnancy
Consult a doctor
Brands
Peridex, PerioGard
Protein binding
~87%
PubChem CID
9552076
MedlinePlus
a682947
ChEBI
CHEBI:3614
ATC code
A01AB03
DrugBank
DB00878
KEGG
D03772
Routes of administration
Oral rinse
Directions
Use Peridex mouthwash as directed by your dentist.
Recommended dosing: Rinse your mouth with 15 mL of Peridex twice a day (morning and evening after brushing your teeth) for 30 seconds. Avoid rinsing your mouth with water or other mouthwashes, brushing your teeth, eating, or drinking for 30 minutes after using Peridex.
Store Peridex between 20oC and 25oC (68oF and 77oF) and away from children’s reach.
For more information on how to use Peridex, refer to the medication guide that comes with your Peridex prescription.
If any questions or concerns arise, contact your dentist.
Ingredients
The active ingredient in Peridex is chlorhexidine gluconate. Its base includes water, alcohol, glycerine, PEG-40 sorbitan di- isostearate, flavour, saccharin sodium, and FD&C Blue #1 Dye.
Contraindications
Patients who are allergic to chlorhexidine gluconate or to any of the other ingredients in Peridex should not use it.
Cautions
- Before you begin using Peridex, inform your dentist of:
- All the prescription and over-the-counter medications you take
- Any mouthwashes you use
- Your allergies
- Your current health problems and past medical history
- Your pregnancy or breastfeeding status
- Peridex contains the following warnings and precautions:
- It is not known whether Peridex has an effect on periodontitis.
- Clinical testing in Peridex users demonstrated an increase in supragingival calculus compared with control users; however, it is unknown whether Peridex increases supragingival calculus. Calculus deposits should be removed every 6 months or less via dental prophylaxis.
- Serious allergic reactions, including anaphylaxis, can occur.
- Staining on teeth, restorations, and tongue can occur, which may be removed by dental prophylaxis. However, permanent discoloration may occur, especially in patients with anterior facial restorations with rough surfaces and margins, and replacements may be needed. Therefore, patients should not use Peridex if permanent discoloration is not acceptable.
- Changes in taste can occur.
Side Effects
Staining of the teeth and other oral surfaces, calculus formation, and changes in taste are the most common Peridex side effects; however, patients may experience other side effects.
Immediately contact your doctor or dentist if you have side effects that bother you or won’t go away.
You can buy Peridex right here.
References
- Peridex. St. Paul, MN: 3M ESPE Dental Products; 2013.
- Peridex Oral Rinse. London, ON: 3M Canada Company Dental Products; 2007.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 291
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