Osnuvo (Teriparatide)
What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
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Prescription Required
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Product Details
Description
Osnuvo (teriparatide) is an injectable medication prescribed to treat severe bone loss, or osteoporosis, in men and postmenopausal women.
Osnuvo 250 mcg/mL cartridges should be placed in an injectable pen for use.
Fact Table
Formula
C181H291N55O51S4
License
US FDA, EMA
Bioavailability
95%
Legal status
Prescription only
Chemical Name
Teriparatide
Elimination half-life
1 hour
Dosage (Strength)
20 mcg/80 µL
Pregnancy
Consult a doctor
Brands
Forteo, Forsteo, Terrosa, Osnuvo
Protein binding
Low
PubChem CID
16129613
MedlinePlus
a603014
ChEBI
63641
ATC code
H05AA02
DrugBank
DB06285
KEGG
D02027
Routes of administration
Subcutaneous
Directions
Your healthcare provider will determine an appropriate Osnuvo (teriparatide) dose for you. You or your caregiver should receive proper training on how to prepare, inject, and dispose of Osnuvo injection.
Osnuvo is given as an injection underneath the skin of the thigh or abdomen.
Never share needles or pens with other people.
For more information about how to use Osnovu, refer to the medication guide that comes with your prescription. If you have any questions or concerns, talk to your healthcare provider or pharmacist.
Storing Osnuvo:
Store Osnuvo pens and new cartridges in the refrigerator between 2°C and 8°C. Avoid freezing. Avoid using if the solution appears cloudy or colored, if you see solid particles in the solution, or if the medication has expired.
Ingredients
The active ingredient in Osnuvo is teriparatide. Inactive ingredients include acetic acid (glacial), mannitol, metacresol, hydrochloric acid (for pH adjustment), sodium acetate (trihydrate), sodium hydroxide (for pH adjustment), and water for injection.
Contraindications
Patients with any of the following should not receive Osnuvo:
- An allergy to any of Osnuvo’s ingredients
- Pregnant or breastfeeding
- Bone cancer or cancer from other parts of the body that has spread to the bone
- History of external beam or implant radiation therapy involving bones
- High calcium levels in the blood
- Bone diseases such as hyperparathyroidism and Paget’s disease
- Severe kidney problems
- Unexplained high alkaline phosphatase levels
Additionally, children or growing adults should not receive Osnuvo.
Cautions
- Before you begin receiving Osnuvo, talk to a healthcare provider about:
- All the prescription and over-the-counter medications you take
- Your allergies
- Your current health problems and past medical history
- Your pregnancy or breastfeeding status
- Blood and urine calcium levels should be monitored during treatment with Osnuvo. Immediately inform your healthcare provider if you have nausea, vomiting, constipation, muscle weakness, or low energy, as these could be symptoms of high calcium levels.
- It is unknown whether using Osnuvo for more than 24 months is safe and effective.
- You may require special monitoring if you have or have a history of kidney or bladder stones. Consult with your healthcare provider.
- Dosing and efficacy of Osnuvo may be affected by kidney function. Consult with your healthcare provider about any monitoring you may need.
- Low blood pressure can occur within 4 hours of taking Osnuvo. If you experience dizziness or lightheadedness after receiving Osnuvo, sit or lie down until you feel better. Contact your healthcare provider if your symptoms worsen or do not go away. Avoid driving or operating machinery until you do not feel dizzy or lightheaded.
- Breastfeeding women should not use Osnuvo, as it has not been determined if the medication passes into breast milk.
Side Effects
Constipation, cough, diarrhea, dizziness, headache, heartburn, high blood pressure, increased sweating, joint pain, leg cramps, nausea, pain, runny nose, sore throat, trouble sleeping, and vomiting are some Osnuvo side effects. However, other side effects may also occur. Immediately inform your healthcare provider of side effects that bother you or won’t go away.
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Reference:
Osnuvo. MedBroadcast.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 14442
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