Orgalutran (Ganirelix)

What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

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Prescription Required

  • Product Details

    Description

    Orgalutran is a prescription medication that plays a vital role in fertility treatment. A fertility specialist may prescribe it for managing ovarian stimulation in assisted reproductive methods, including in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI).

    Ganirelix, the active ingredient in Orgalutran, works by inhibiting early luteinizing hormone (LH) surges. This is crucial to prevent premature ovulation before eggs are adequately developed. Through this action, Orgalutran ensures precise control over ovulation timing.

    Directions

    Fertility specialists exclusively prescribe and oversee Orgalutran's usage. 

    Its dosing and timing are tailored to each patient's unique response to ovarian stimulation, aiming to optimize the success of egg retrieval.

    Ingredients

    Orgalutran contains ganirelix as its active component. Inactive ingredients comprise glacial acetic acid, mannitol, and water for injection, adjusted to pH 5.0 with acetic acid or sodium hydroxide. 

    The medication is available as a 250 microgram/0.5 mL solution.

    Interactions

    Common drug-drug interactions may include:

    • Flotufolastat F18
    • Gallium Ga 68 PSMA-11
    • Indium 111 Capromab Pendetide
    • Piflufolastat F18

    Cautions

    Regular communication with your fertility specialist remains crucial during Orgalutran treatment. They will closely monitor your response and potential side effects to make necessary adjustments. If any side effects occur, even though they are uncommon, informing your healthcare provider is essential.

    It's important to avoid Orgalutran if you have a known hypersensitivity to ganirelix or its ingredients. Mention any latex allergies to your doctor, as the packaging might contain latex. 

    History of kidney or liver disease should be disclosed before starting therapy.

    If you become pregnant, discontinue Orgalutran immediately. Common side effects encompass abdominal pain, headache, injection-site reactions, and more.

    Side Effects

    Common adverse reactions include:

    • Abdominal pain
    • Anaphylactic shock
    • Anaphylaxis
    • Angioedema
    • Headache
    • Hypersensitivity reaction
    • Injection-site reaction
    • Nausea
    • Nonimmune anaphylaxis
    • Ovarian hyperstimulation syndrome
    • Pelvic pain
    • Urticaria
    • Vaginal hemorrhage

    References

    Orgalutran [Patient Medication Information]. Organon; 2021.



    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 10231

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