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Opdivo (Nivolumab)

What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

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  • Product Details

    Description

    Opdivo (nivolumab) is a medication used to treat certain types of cancer, including:

    • Melanoma
    • Non-Small Cell Lung Cancer
    • Malignant Pleural Mesothelioma
    • Advanced Kidney Cancer
    • Classical Hodgkin Lymphoma
    • Head and Neck Squamous Cell Cancer
    • Bladder or Urinary Tract Cancer (Urothelial)
    • Colorectal Cancer
    • Advanced Liver Cancer
    • Gastric, Gastroesophageal Junction, and Esophageal Cancers

    Directions

    Your healthcare provider will determine an appropriate treatment regimen for you based on your age, weight, medical conditions, and type of cancer you have. Blood tests will also be checked by your healthcare provider.

    Your healthcare provider will administer Opdivo intravenous infusion.

    If you have any questions or concerns, consult your healthcare provider.

    Ingredients

    Nivolumab is the active ingredient in Opdivo. The inactive ingredients include mannitol, pentetic acid, polysorbate 80, sodium chloride, sodium citrate dihydrate, and Water for Injection. Opdivo may also contain hydrochloric acid and/or sodium hydroxide.

    Contraindications

    There are no contraindications to Opdivo per the most recent Prescribing Information. However, talk to your healthcare provider about a treatment regimen that is best for you.

    Cautions

    • Before you start treatment with Opdivo, consult with your healthcare provider about:
      • All the prescription and nonprescription medications you take
      • Your allergies
      • Your current health problems and past medical history
      • Your pregnancy or breastfeeding status
    • Immune system problems that can be severe or result in death may occur.
    • Infusion-related reactions may occur.
    • Serious and potentially fatal complications may occur in patients who receive a stem cell transplant that uses donor stem cells (allogeneic) before or after receiving Opdivo.
    • Opdivo use can cause harm to an unborn baby. Effective contraception should be used.
    • Women should not breastfeed while being treated with Opdivo.
    • Patients with multiple myeloma should not receive Opdivo in combination with a thalidomide analogue plus dexamethasone unless they are part of a controlled clinical trial.

    Side Effects

    Fatigue; rash; muscle, bone, and joint pain; itchy skin; diarrhea; nausea; weakness; cough; vomiting; shortness of breath; constipation; decreased appetite; back pain; upper respiratory tract infection; fever; headache; stomach pain; and urinary tract infection are some common Opdivo side effects. However, other side effects can also occur. Call your healthcare provider right away if you have side effects that bother you or won’t go away.

    Ask your healthcare provider about Opdivo.

    Reference

    1. Opdivo. Princeton, NJ: Bristol-Myers Squibb Company; 2023.


    Dr Savannah Muncy
    About Dr. Savannah Muncy (Page Author)


    Dr. Muncy (PharmD) studied science and education as an undergraduate before attending the Appalachian College of Pharmacy where she completed her PharmD in three years. She is currently using her pharmacy and healthcare expertise to write medical content for clients all around the world. She is focused on delivering the most current, accurate, and engaging information to healthcare professionals and patients. Read More....


    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 14386

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