What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Norprolac (Quinagolide)
Prescription Required
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Product Details
Description
If you experience hyperprolactinemia, then your doctor may prescribe Norprolac. Hyperprolactinemia is characterized by elevated levels of prolactin hormone in the blood. Hyperprolactinemia can cause various symptoms, including irregular menstrual periods, infertility, and breast milk production in non-pregnant women.
Norprolac contains quinagolide, a dopamine agonist that works by binding to dopamine receptors in the brain, reducing the production and release of prolactin. By normalizing prolactin levels, Norprolac helps alleviate the associated symptoms.
Fact Table
Formula
C20H33N3O3S
License
US DailyMed
Bioavailability
4 %
Legal status
Rx-Only
Chemical Name
Quinagolide
Elimination half-life
11.5 hours
Dosage (Strength)
75mcg
Pregnancy
Consult Doctor
Brands
Norprolac
Protein binding
90%
PubChem CID
55645
MedlinePlus
No Data Available
ChEBI
No Data Available
ATC code
G02CB04
DrugBank
DBSALT001152
KEGG
D07217
Routes of administration
Oral
Directions
The starting dosage of quinagolide is 0.025 mg once daily for three days before increasing it to 0.05 mg once daily for three days.
Starting week two, increase the dosage to 0.075 mg once daily. The usual dosage range is 0.075-0.15 mg daily. The maximum dosage is 0.9 mg daily.
Ingredients
The active ingredient in norprolac is quinagolide.
Interactions
Common drug-drug interactions can include
- Alcohol
- Antipsychotic Agents
- Blood Pressure Lowering Agents
- Bromopride
- Metoclopramide
- Pipamperone
- Sulpiride
Cautions
Tell your doctor if you have a history of liver or kidney problems, heart disease, or a history of fibrotic disorders.
Norprolac can increase the risk of nausea and vomiting.
Tell your doctor if you experience low blood pressure during treatment. Blood pressure should be frequently monitored.
Tell your healthcare team if you suddenly develop the onset of impulse control disorders like pathological gambling, hypersexuality, or compulsive spending.
The medication may cause dizziness or low blood pressure, so use caution when driving or operating machinery.
Side Effects
Common side effects may include:
- Abdominal distress
- Abdominal pain
- Acute psychosis
- Anorexia
- Asthenia
- Constipation
- Decreased hematocrit
- Decreased hemoglobin
- Diarrhea
- Dizziness
- Drowsiness
- Dyspepsia
- Edema
- Emotional lability
- Eye disease
- Fatigue
- Flushing
- Headache
- Hypotension
- Increased creatinine phosphokinase
- Increased serum bilirubin
- Increased serum potassium
- Increased serum transaminases
- Insomnia
- Lack of concentration
- Limb pain
- Malaise
- Mastalgia
- Nausea
- Nasal congestion
- Palpitations
- Sedated state
- Syncope
- Vomiting
- Weight gain
References
Norprolac [package insert]. Toronto, Ontario: Ferring Inc.; 2013.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 12835
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