Description
Myrbetriq is used to treat adults who have overactive bladder (OAB) with symptoms of urinary incontinence, urgency, and urinary frequency.
It is also used to treat neurogenic detrusor overactivity (NDO) in pediatric patients who are at least 3 years old and weigh at least 35 kg.
Myrbetriq 25 mg extended-release oral tablets and Myrbetriq 50 mg extended-release oral tablets (mirabegron extended-release tablets) are available with a valid prescription.
Fact Table
|
Formula
|
C21H24N4O2S
|
License
|
US FDA
|
Bioavailability
|
29-35%
|
Legal status
|
Prescription only (Rx)
|
Chemical Name
|
Mirabegron
|
Elimination half-life
|
50 hours
|
Dosage (Strength)
|
25 mg, 50 mg extended-release tablets
|
Pregnancy
|
Consult a doctor
|
Brands
|
Myrbetriq
|
Protein binding
|
71%
|
PubChem CID
|
9869929
|
MedlinePlus
|
a612045
|
ChEBI
|
CHEBI:70720
|
ATC code
|
G04BD12
|
DrugBank
|
DB04899
|
KEGG
|
D08560
|
Routes of administration
|
Oral
|
Directions
Take Myrbetriq exactly as prescribed by your doctor. For additional instructions for use, refer to the medication guide that accompanies your prescription.
Recommended starting dose for adults with OAB: Take 25 mg by mouth once a day. The dose may be increased to 50 mg by mouth once a day after 4-8 weeks.
Recommended dosing for pediatric patients with NDO is based on weight and will be determined by the doctor.
Store Myrbetriq extended-release tablets between 20°C and 25°C (68°F and 77°F).
If you have any questions or concerns, talk to your doctor.
Ingredients
The active ingredient in Myrbetriq is mirabegron.
Inactive ingredients in Myrbetriq tablets include butylated hydroxytoluene, hydroxypropyl cellulose, hypromellose, magnesium stearate, polyethylene glycol, polyethylene oxide, red ferric oxide (25 mg tablet only), and yellow ferric oxide.
Contraindications
Patients with an allergy to mirabegron or to any of the inactive ingredients in Myrbetriq should not take it.
Cautions
- Before you begin Myrbetriq treatment, tell your doctor about:
- All the prescription and over-the-counter medications you take
- Your allergies
- Your current health problems and past medical history
- Your pregnancy or breastfeeding status
- Myrbetriq is associated with several warnings and precautions:
- High blood pressure
- Urinary retention in patients who have bladder outlet obstruction or are being treated with muscarinic antagonist medications for OAB
- Angioedema, or swelling under the skin, of the face, tongue, lips, and/or larynx
Side Effects
High blood pressure, common cold, headache, urinary tract infection, dry mouth, constipation, and rapid heart rate are common Myrbetriq side effects. Immediately call your doctor if you experience side effects that bother you or won’t go away.
You can buy Myrbetriq right here.
Reference
Myrbetriq. Northbrook, IL: Astellas Pharma US, Inc.; 2021.
About Dr. Savannah Muncy (Page Author)
Dr. Muncy (PharmD) studied science and education as an undergraduate before attending the Appalachian College of Pharmacy where she completed her PharmD in three years. She is currently using her pharmacy and healthcare expertise to write medical content for clients all around the world. She is focused on delivering the most current, accurate, and engaging information to healthcare professionals and patients. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 13162