What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Myfembree (Relugolix/Estradiol/Norethindrone Aceta
Also Known as Ryeqo
Prescription Required
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Product Details
Description
Myfembree is a prescription medication that is taken by postmenopausal women to manage heavy menstrual bleeding related to uterine fibroids and moderate to severe pain related to endometriosis.
Myfembree comes in oral tablets containing relugolix 40 mg, estradiol 1 mg, and norethindrone acetate 0.5 mg.
Directions
Take Myfembree exactly as prescribed by your doctor. Carefully read the information that comes with your prescription. Talk to your doctor or pharmacist about any questions or concerns you may have.
Recommended dosing: Take one tablet by mouth once daily.
Store at 15°C to 30°C (59°F to 86°F) and out of reach of children.
Ingredients
Relugolix (GnRH receptor antagonist), estradiol (estrogen), and norethindrone acetate (progestin) are the active ingredients in Myfembree. The inactive ingredients include hydroxypropyl cellulose, hypromellose, iron oxide yellow, lactose monohydrate, mannitol, magnesium stearate, sodium starch glycolate, titanium dioxide, and triacetin.
Contraindications
Patients with any of the following should not take Myfembree:
- High risk of blood clots or blood clotting problems
- Pregnant
- Osteoporosis
- Current or history of breast cancer or other hormone-sensitive cancers
- Liver problems or disease
- Undiagnosed abnormal vaginal bleeding
- Allergy to any of the ingredients or excipients in the medication
Cautions
Myfembree contains the following FDA Boxed Warning:
- Estrogen and progestin combinations, including Myfembree, increase the risk of blood clotting problems, especially in women at increased risk for these events.
- Myfembree should not be used in women with current or a history of blood clotting problems and in women at increased risk for these events, including women older than 35 years of age who smoke or women with uncontrolled high blood pressure.
- Before you start taking Myfembree, talk to your doctor about:
- All the prescription and over-the-counter medications you take
- Your allergies
- Your current health problems and past medical history
- Your pregnancy or breastfeeding status
- Blood clotting or vision problems may occur.
- Potentially irreversible bone density loss can occur.
- Suicidal ideation and mood problems, including depression, can occur. Patients should seek emergency care right away if they have new or worsening depression, anxiety, or other mood changes.
- Liver damage can occur.
- Women with uncontrolled high blood pressure should not take Myfembree, as the medication can increase blood pressure.
- Non-hormonal contraception is recommended during treatment with Myfembree and for one week after stopping Myfembree. Myfembree alters menstrual bleeding and may delay the ability to recognize pregnancy.
- Early pregnancy loss can occur. Non-hormonal contraception is recommended during treatment.
- Uterine fibroid prolapse or expulsion can occur. Patients should seek emergency care right away if they have severe uterine bleeding.
- Myfembree should be stopped if an allergic reaction occurs.
Side Effects
Hot flashes, uterine bleeding, hair loss, decreased sex drive, headache, mood changes, nausea, toothache, back pain, joint pain, fatigue, and dizziness are some Myfembree side effects. However, these are not all the side effects that can occur. Contact your doctor right away if you have side effects that bother you or won’t go away.
Here, you can buy Myfembree at a competitive price.
Reference
- Myfembree. Brisbane, CA: Myovant Sciences, Inc.; 2023.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13857
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