What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Mycobutin (Rifabutin)
Prescription Required
We don't have this generic product yet!
Sign up to get exclusive coupon discounts and be the first to be notified when we have this product available.
-
Product Details
Description
Mycobutin, also called Rifabutin, is an antibiotic classified under the rifamycin group of antimycobacterial medications. It works by blocking bacterial growth through targeting RNA synthesis in bacteria, thereby hindering their reproduction and survival. Rifabutin comes as an oral capsule used to prevent and treat infections caused by Mycobacterium avium complex (MAC) in individuals with HIV. MAC is a frequent opportunistic infection in individuals with weakened immune systems.
Directions
Mycobutin is typically administered orally, with a standard adult dosage usually set at 300 mg once daily. The specific dosage may vary depending on the patient's weight, medical condition, and response to treatment. Patients should swallow the capsules whole to prevent irritation of the mouth or throat. It’s important to follow the prescribed instructions carefully and not alter the dose without consulting a healthcare provider.
Ingredients
Mycobutin includes both active and inactive components. The active ingredient in Mycobutin capsules is Rifabutin, which is a semi-synthetic antibiotic.
Contraindications
Avoid taking or using this medication if you have a history of allergic reactions to Rifabutin or any other rifamycins.
Cautions
- Before using Mycobutin, ensure you provide your healthcare provider with the following information:
- Existing health conditions
- Known allergies
- A list of all the medications you are currently taking
- Your pregnancy or breastfeeding status
- Do not use Mycobutin alone for active tuberculosis as it could lead to drug-resistant tuberculosis. It should be combined with other tuberculosis medications.
- If Mycobutin is used with clarithromycin for treating Mycobacterium avium complex, the dose of Mycobutin should be reduced to prevent high blood levels.
- Be alert for signs of allergic reactions like severe allergies or flu-like symptoms. If these occur, stop taking Mycobutin and seek medical attention.
- Monitor for signs of uveitis, especially when taken with clarithromycin or antifungals. If eye inflammation is suspected, see an ophthalmologist and consider stopping Mycobutin.
- Clostridioides difficile associated diarrhea can occur with Mycobutin use. Monitor for diarrhea and manage with appropriate interventions if necessary.
- Watch for serious skin reactions like Stevens-Johnson syndrome. Stop Mycobutin if severe skin reactions develop and seek medical care.
Side Effects
Mycobutin side effects may include stomach pain, fever, headaches, and a general feeling of discomfort. Patients might also experience digestive disturbances like nausea, diarrhea, and indigestion, as well as respiratory symptoms like cough and sore throat. Other frequent side effects include muscle or joint pain and changes in blood cell counts, specifically leukopenia and anemia.
More significant concerns with Mycobutin include neutropenia, which can increase the risk of infections, and thrombocytopenia, which can lead to bleeding problems. Rare but severe complications such as thrombotic thrombocytopenic purpura have been noted, which can be life-threatening. Mycobutin can also cause hypersensitivity reactions, characterized by rash and trouble breathing, requiring urgent medical attention. Gastrointestinal disorders like Clostridioides difficile colitis, a serious intestinal condition, have been reported. Patients should monitor for symptoms of serious side effects and seek immediate medical care if they occur.
References:
- Mycobutin (Rifabutin) Product Monograph. New York, NY: Pfizer Laboratories; 2021.
- Mycobutin (Rifabutin) Drug Label Information. New York, NY: Pfizer Laboratories; 2021.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 1661
-
Product Reviews
