Description
Your doctor may prescribe Mirapex ER to treat Parkinson's disease.
Parkinson's disease is a chronic condition that typically develops in adults aged 60 years or older. Symptoms can affect all systems in the body and may include:
- Difficulty speaking
- Difficulty walking
- Dizziness
- Fatigue
- Muscle rigidity
- Problems with coordination
- Slow bodily movement
- Stiff muscles
- Tremor
Mirapex ER is a dopamine agonist that works by binding to D2 dopamine receptors, which stimulates the activity of cells in the nervous system. Activating dopamine receptors helps to reduce the symptoms of Parkinson's disease.
Fact Table |
Formula |
C10H17N3S |
License |
US FDA, EU EMA |
Bioavailability |
More than 90% |
Legal status |
Rx-only |
Chemical Name |
Pramipexole |
Elimination half-life |
8–12 hours |
Dosage (Strength) |
0.375mg, 0.75mg, 1.5mg, 3.0mg |
Pregnancy |
No Known Risk |
Brands |
Mirapex, Mirapexin, Sifrol |
Protein binding |
15% |
PubChem CID |
119570 |
MedlinePlus |
a697029 |
ChEBI |
8356 |
ATC code |
N04BC05 |
DrugBank |
DB00413 |
KEGG |
D05575 |
Routes of administration |
By mouth |
Directions
Once you have your prescription and buy Mirapriex ER, the starting Mirapex ER dosage is 0.375 mg taken orally once daily.
The maximum recommended dose is 4.5 mg taken orally once daily.
Ingredients
The active ingredient in Mirapex ER is pramipexole.
Interactions
Common drug-drug interactions with this medication can include:
- Alizapride
- Amifostine
- Amisulpride
- Antipsychotic Agents (First Generation)
- Antipsychotic Agents (Second Generation)
- Bromperidol
- Fexinidazole
- Methotrimeprazine
- Metoclopramide
- Obinutuzumab
- Risdiplam
- Sulpiride
- Tafenoquine
Cautions
Once you are prescribed and buy Mirapex ER, use caution if you have a history of low blood pressure.
Mirapex ER can cause problems with impulse control.
Use caution if you have a history of kidney problems.
Hallucinations may occur while using this drug and are more likely in older adults.
Side Effects
Potential adverse reactions with this drug can include:
- Abnormal dreams
- Abnormal gait
- Accidental injury
- Amnesia
- Anorexia
- Asthenia
- Chest pain
- Confusion
- Constipation
- Dermatologic disorders
- Diarrhea
- Dizziness
- Drowsiness
- Dyskinesia
- Dyspnea
- Dystonia
- Edema
- Extrapyramidal reaction
- Falling
- Fatigue
- Hallucination
- Headache
- Hypertonia
- Impulse control disorder
- Influenza
- Insomnia
- Limb pain
- Muscle spasm
- Nasal congestion
- Nausea
- Orthostatic hypotension
- Peripheral edema
- Restless leg syndrome
- Sleep disorder
- Upper abdominal pain
- Urinary frequency
- Vertigo
- Vomiting
- Weight loss
- Xerostomia
References
Mirapex ER [package insert]. Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc. ; 2014.
Frequently Asked Questions about Mirapex ER
What is Mirapex ER?
Mirapex ER is a prescription medication used to treat the symptoms of Parkinson's disease. It contains the active ingredient Pramipexole in an extended-release form, which provides continuous relief from Parkinson's symptoms.
How does Mirapex ER work?
Mirapex ER works by acting on specific dopamine receptors in the brain. It helps improve the control of muscle movements, reduce tremors, and alleviate other symptoms associated with Parkinson's disease.
When is Mirapex ER prescribed?
Mirapex ER is prescribed for individuals diagnosed with Parkinson's disease. It may be used alone or in combination with other medications as determined by a healthcare provider.
What is the recommended dosage of Mirapex ER?
The dosage of Mirapex ER varies depending on individual needs and the stage of Parkinson's disease. Your doctor will prescribe the appropriate dose, and it's essential to follow their instructions carefully.
Are there any common side effects of Mirapex ER?
Yes, some common side effects may include dizziness, drowsiness, nausea, constipation, or difficulty sleeping. These side effects can vary from person to person.
Can Mirapex ER be used in elderly patients?
Mirapex ER can be used in elderly patients; however, the dosage may need to be adjusted based on individual health and tolerance. Consult with a healthcare provider for proper guidance.
Is it safe to drive or operate machinery while taking Mirapex ER?
Mirapex ER may cause drowsiness or dizziness as side effects. It's essential to wait until you are sure about your alertness before engaging in activities that require full concentration, such as driving or operating heavy machinery.
Can Mirapex ER be taken with food?
Mirapex ER can be taken with or without food. However, taking it with food may help reduce the risk of stomach upset in some individuals.
What should I do if I miss a dose of Mirapex ER?
If you miss a dose, take it as soon as you remember. However, if it's close to the time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
Is Mirapex ER safe for use during pregnancy or breastfeeding?
It's important to discuss the use of Mirapex ER with your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. They will evaluate the potential risks and benefits in your specific situation.
About Dr. Conor Sheehy (Page Author)
Dr. Sheehy (BSc Molecular Biology, PharmD) works a clinical pharmacist specializing in cardiology, oncology, and ambulatory care. He’s a board-certified pharmacotherapy specialist (BCPS), and his experience working one-on-one with patients to fine tune their medication and therapy plans for optimal results makes him a valuable subject matter expert for our pharmacy. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 11498