What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Mayzent (Siponimod)

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Brand

Mayzent (Siponimod)

Prescription Required

Strength
Qty
0.25mg
2mg

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  • Product Details

    Description

    Mayzent (siponimod) is a prescription medication for adults with relapsing forms of multiple sclerosis.

    Mayzent is available as an oral tablet in 0.25 mg, 1 mg, and 2 mg strengths.

    Fact Table

    Formula

    C29H35F3N2O3

    License

    US FDA, EMA

    Bioavailability

    84%

    Legal status

    Prescription only

    Chemical Name

    Siponimod

    Elimination half-life

    30 hours

    Dosage (Strength)

    0.25 mg, 2 mg tablets

    Pregnancy

    Consult a doctor

    Brands

    Mayzent

    Protein binding

    99.9%

    PubChem CID

    23724360

    MedlinePlus

    a618044

    ChEBI

    63640

    ATC code

    L04AA42

    DrugBank

    DB11693

    KEGG

    D10547

    Routes of administration

    Oral

    Directions

    Take Mayzent exactly as prescribed by your doctor. Carefully read the medication guide that comes with your prescription.

    Mayzent dosing:

    Your doctor will determine an appropriate starting dose for you and will adjust dosing to the recommended maintenance dosage. Do not crush, split, or chew the tablets.

    Mayzent storage:

    Keep Mayzent tablets at room temperature between 68°F and 77°F (20°C and 25°C) for a maximum of 3 months. You may keep unopened Mayzent tablets in the refrigerator between 36°F and 46°F (2°C to 8°C) if you need to store them for longer than 3 months. However, once the containers have been opened, do not place them back in the refrigerator.

    Store the medication out of reach of children.

    If you have any questions or concerns about Mayzent, contact your doctor or pharmacist.

    Ingredients

    The active ingredient in Mayzent is siponimod.

    Inactive ingredients include colloidal silicon dioxide, crospovidone, glyceryl dibehenate, lactose monohydrate, microcrystalline cellulose, with a film coating containing iron oxides (black and red iron oxides for the 0.25 mg and 1 mg strengths and red and yellow iron oxides for the 2 mg strength), lecithin (soy), polyvinyl alcohol, talc, titanium dioxide, and xanthan gum.

    Contraindications

    Patients with any of the following should not receive Mayzent:

    • A CYP2C9*3/*3 genotype
    • Had a heart attack, unstable angina (a type of chest pain), stroke, mini stroke, hospitalized with decompensated heart failure, or Class III/IV heart failure within in the past 6 months
    • Mobitz type II second-degree, third-degree AV block, or sick sinus syndrome, unless the patient has a functioning pacemaker

    Cautions

    • Before you begin taking Mayzent, talk to your doctor about:
      • All the prescription and over-the-counter medications you take
      • Your allergies
      • Your current health problems and past medical history
      • Your pregnancy or breastfeeding status
    • Mayzent is associated with the following warnings and precautions:
      • Increased risk of infections
      • Progressive multifocal leukoencephalopathy
      • Macular edema
      • Decreased heart rate and atrioventricular conduction delays
      • Respiratory problems
      • Liver problems
      • Skin cancer
      • High blood pressure
      • Harm to an unborn baby; effective contraception is recommended for female patients during treatment and for 10 days after stopping treatment with Mayzent
    • Live vaccines should not be given to patients while they are receiving treatment with Mayzent and for up to 4 weeks after treatment.

    Side Effects

    Headache, high blood pressure, and increases in liver enzymes are common Mayzent side effects. However, other side effects may also occur. Immediately inform your doctor of side effects that bother you or won’t go away.

    You can buy Mayzent right here!

    Reference:

    Mayzent. East Hanover, NJ: Novartis Pharmaceuticals Corporation; 2023.




    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 14549

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