Description
MAVIK (trandolapril) is a prescription medication used to lower high blood pressure. Since high blood pressure is a component of several diseases, it can be used to treat the following:
- Heart failure with reduced ejection fraction (HFrEF)
- Hypertension
- Left ventricular dysfunction
- Post- heart attack heart failure
MAVIK is a type of medication called an ACE inhibitor. It prevents the conversion of angiotensin I to angiotensin II, which decreases blood pressure. MAVIK is converted to its active form in the liver.
Fact Table |
Formula |
C24H34N2O5 |
License |
US FDA |
Bioavailability |
10% |
Legal status |
Rx-only |
Chemical Name |
Trandolapril |
Elimination half-life |
6 hours |
Dosage (Strength) |
1mg, 2mg, 4mg |
Pregnancy |
Not Recommended |
Brands |
Mavik |
Protein binding |
80% |
PubChem CID |
5484727 |
MedlinePlus |
a697010 |
ChEBI |
9649 |
ATC code |
C09AA10 |
DrugBank |
DB00519 |
KEGG |
D00383 |
Routes of administration |
By mouth |
Directions
Take MAVIK exactly as prescribed by your healthcare provider. It should be taken once daily on an empty stomach.
The initial dose of MAVIK is 1 mg by mouth once daily. The dose should be increased to a maximum dose of 4 mg by mouth once daily.
MAVIK is available in 1 mg, 2 mg, and 4 mg tablets.
Ingredients
The active ingredient in MAVIK is trandolapril.
Interactions
Common drug-drug interactions with MAVIK may include:
- Aliskiren
- Amifostine
- Angiotensin II receptors blockers
- Bromperidol
- Grass pollen allergen extract
- Iron dextran complex
- Lanthanum
- Lithium
- Obinutuzumab
- Sacubitril
- Sodium phosphates
Cautions
Do not take MAVIK if you are pregnant or breastfeeding. MAVIK is toxic to the developing fetus and should be stopped as soon as pregnancy is detected.
Tell your doctor if you develop a dry cough while taking MAVIK.
Your doctor should monitor for increased blood potassium while you are taking MAVIK.
Tell your doctor if you have a history of kidney or liver dysfunction.
Tell your doctor if you have a history of cardiovascular disease before starting MAVIK.
Side Effects
MAVIK (trandolapril) side effects may include:
- Bradycardia
- Cardiogenic shock
- Cerebrovascular accident
- Cough
- Diarrhea
- Dizziness
- Gastritis
- Hyperkalemia
- Hypocalcemia
- Hypotension
- Increased kidney enzymes
- Increased uric acid
- Intermittent claudication
- Myalgia
- Syncope
- Weakness
References
Mavik [package insert]. Chicago, IL: Abbot; 2011.
Frequently Asked Questions about Mavik (Trandolapril)
What is Mavik (Trandolapril)?
Mavik is a prescription medication that contains the active ingredient Trandolapril. It belongs to a class of drugs known as ACE inhibitors and is primarily used to treat high blood pressure (hypertension) and heart failure.
How Does Mavik (Trandolapril) Work?
Mavik works by relaxing blood vessels, which helps lower blood pressure. It also reduces the workload on the heart, making it an effective treatment for heart failure.
Can Mavik (Trandolapril) Be Used for High Blood Pressure Alone?
Yes, Mavik is commonly prescribed for high blood pressure (hypertension) as a standalone treatment. However, it may also be part of a combination therapy if necessary.
Is Mavik (Trandolapril) Available Over-the-Counter (OTC)?
No, Mavik is not available over-the-counter. It is a prescription medication, and you must consult a healthcare provider to obtain it.
What Is the Recommended Dosage for Mavik (Trandolapril)?
The recommended dosage of Mavik (Trandolapril) can vary depending on the individual and their specific medical condition. Your healthcare provider will determine the appropriate dosage for you.
Are There Any Common Side Effects Associated with Mavik (Trandolapril)?
Like many medications, Mavik may have side effects. Common side effects can include dizziness, cough, headache, and changes in taste. It's important to discuss potential side effects with your healthcare provider.
Can I Take Other Medications Alongside Mavik (Trandolapril)?
It's important to inform your healthcare provider about all the medications, supplements, or herbal remedies you are taking, as some may interact with Mavik and affect its effectiveness.
Is It Safe to Use Mavik (Trandolapril) During Pregnancy?
Mavik should not be used during pregnancy, especially during the second and third trimesters, as it can harm the unborn baby. If you are pregnant or planning to become pregnant, consult your healthcare provider for alternative treatment options.
Can Mavik (Trandolapril) Be Taken While Breastfeeding?
It's important to discuss the use of Mavik while breastfeeding with your healthcare provider. They will assess the potential benefits and risks and provide guidance on its use during this period.
How Often Will I Need to Monitor My Blood Pressure While Taking Mavik (Trandolapril)?
Your healthcare provider will determine how often you should monitor your blood pressure while taking Mavik. Regular monitoring is essential to ensure the medication is effectively controlling your blood pressure.
About Dr. Conor Sheehy (Page Author)
Dr. Sheehy (BSc Molecular Biology, PharmD) works a clinical pharmacist specializing in cardiology, oncology, and ambulatory care. He’s a board-certified pharmacotherapy specialist (BCPS), and his experience working one-on-one with patients to fine tune their medication and therapy plans for optimal results makes him a valuable subject matter expert for our pharmacy. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 2428