What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Ludiomil (Maprotiline)
Prescription Required
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Product Details
Description
Your doctor may prescribe Ludiomil used to treat depression. Classified as a tetracyclic antidepressant, it affects specific brain chemicals involved in mood regulation. It can also be prescribed to treat anxiety associated with depression.
Ludiomil work by increasing levels of norepinephrine, a neurotransmitter responsible for mood and emotions. Ludiomil helps alleviate depressive symptoms and enhance overall well-being. The exact mechanism is not fully understood.
Fact Table
Formula
C20H23N
License
US FDA
Bioavailability
66–70%
Legal status
Rx-Only
Chemical Name
Maprotiline
Elimination half-life
27–58 hours
Dosage (Strength)
25mg, 75mg
Pregnancy
Consult Doctor
Brands
Ludiomil
Protein binding
88%
PubChem CID
4011
MedlinePlus
a682158
ChEBI
6690
ATC code
N06AA21
DrugBank
DB00934
KEGG
D02566
Routes of administration
By mouth
Directions
The starting dosage is 25-75 mg by mouth once or more times a day. Your doctor may increase the dosage every two weeks until an effective dose is found.
The usual effective dosage is 150-225 mg total daily dose.
Ingredients
The active ingredient is maprotiline.
Interactions
Common interactions include:
- Acetylcholinesterase Inhibitors
- Aclidinium
- Alcohol
- Alizapride
- Amantadine
- Anticholinergic Agents
- Azelastine (Nasal)
- Blonanserin
- Botulinum Toxin-Containing Products
- Brexanolone
- Brimonidine (Topical)
- Bromopride
- Bromperidol
- Buprenorphine
- Cannabinoid-Containing Products
- Chloral Betaine
- Chlormethiazole
- Chlorphenesin Carbamate
- Cimetropium
- CloZAPine
- CNS Depressants
- Daridorexant
- DexmedeTOMIDine
- Difelikefalin
- Dimethindene (Topical)
- Doxylamine
- DroPERidol
- Eluxadoline
- Esketamine
- Flunarizine
- Flunitrazepam
- Gastrointestinal Agents
- Glucagon
- Glycopyrrolate
- Glycopyrronium (Topical)
- HydrOXYzine
- Ipratropium
- Itopride
- Ixabepilone
- Kava Kava
- Kratom
- Lemborexant
- Levosulpiride
- Levothyroxine
- Lisuride
- Lofexidine
- Magnesium Sulfate
- Methotrimeprazine
- Metoclopramide
- MetyroSINE
- Mianserin
- Minocycline
- Mirabegron
- Monoamine Oxidase Inhibitors
- Nitroglycerin
- Olopatadine
- Opioid Agonists
- Orphenadrine
- Oxatomide
- Oxomemazine
- Oxybate Salt Products
- OxyCODONE
- Paraldehyde
- Perampanel
- Piribedil
- Potassium Chloride
- Potassium Citrate
- Pramipexole
- Pramlintide
- Procarbazine
- Ramosetron
- Revefenacin
- Ropeginterferon Alfa-2b
- ROPINIRole
- Rotigotine
- Rufinamide
- Secretin
Cautions
Tell your doctor if you have a history of seizures, kidney problems, liver problems, or urinary retention.
Ludiomil may cause excessive cause drowsiness or dizziness.
Speak with your doctor or pharmacist for a full list of cautions that apply to you.
Side Effects
Common side effects include:
- Anemia
- Bronchitis
- Cardiac failure
- Cough
- Decreased hemoglobin
- Decreased hematocrit
- Dizziness
- Dyspepsia
- Fatigue
- Flushing
- Fluid retention
- Headache
- Hypersensitivity
- Hypotension
- Increased liver enzymes
- Nasal congestion
- Nausea
- Oligospermia
- Peripheral edema
- Sinusitis
- Vomiting
- Weakness
References
Ludiomil [package insert]. Morgantown, WV: Mylan; 2014.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 5011
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