What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Lotemax SM (loteprednol etabonate ophthalmic gel)

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Brand

Lotemax SM (loteprednol etabonate ophthalmic gel)

Prescription Required

Strength
Qty
3.8mg 5g

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  • Product Details

    Description

    Lotemax SM (Loteprednol Etabonate Ophthalmic Gel) 0.38% is a corticosteroid used for the treatment of inflammation and pain after eye surgery.


    Fact Table

    Formula

    C24H31ClO7

    License

    US FDA

    Bioavailability

    None

    Legal status

    Rx-Only

    Chemical Name

    Loteprednol

    Elimination half-life

    2.8 hrs

    Dosage (Strength)

    3.8mg 5g

    Pregnancy

    Consult Doctor

    Brands

    Lotemax SM

    Protein binding

    95%

    PubChem CID

    444025

    MedlinePlus

    a619025

    ChEBI

    31784

    ATC code

    S01BA14

    DrugBank

    DB14596

    KEGG

    D01689

    Routes of administration

    Eye drops

    Directions

    Lotemax SM is available as a sterile preserved gel for use in the eye only.

    Before instilling the gel into the eye, turn the closed bottle upside down and shake once to fill the tip.

    Instill one drop into the affected eye(s) three times a day for two weeks beginning the day after surgery.

    Ingredients

    Each gram of gel contains 3.8 mg of loteprednol etabonate. 

    Contraindications

    Do not use Lotemax SM if you have a viral eye disease or a bacterial or fungal eye infection.

    Cautions

    • Before you start using Lotemax SM eye gel, inform your doctor:
      • About your allergies
      • About all the medications you take, including other eye drops or eye gels
      • About your health conditions
      • If you are pregnant or plan to become pregnant
      • If you are breastfeeding or plan to breastfeed
    • Using Lotemax SM for a long time can increase your risk for glaucoma or other vision problems. Your intraocular pressure should be checked if you use Lotemax SM for more than 10 days.
    • Tell your doctor if you have cataracts.
    • Lotemax SM may prolong healing time and increase the risk for bleb formation after cataract surgery. 
    • Using Lotemax SM for a long time can increase the risk for secondary eye infections and mask or worsen active purulent infections.
    • Using Lotemax SM for a long time can lengthen the course of or worsen the symptoms of viral eye infections, including herpes simplex.
    • Using Lotemax SM for a long time can increase your risk for fungal eye infections.
    • You should not wear contact lenses when your eyes are inflamed.

    Side Effects

    Lotemax SM may cause blurry vision, light sensitivity, eye swelling, or eye redness. 

    Contact your doctor right away if you experience bothersome or persistent side effects.

    References:

    1. Lotemax SM Prescribing Information. Tampa, FL: Bausch & Lomb Incorporated; 2020.
    2. Loteprednol (Ophthalmic Route). Mayo Clinic. Last updated May 1, 2021. Accessed February 6, 2022.


    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 13612

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