Description
Lorzone (chlorzoxazone) is a medication that is used with rest, physical therapy, and other regimens to treat the sudden onset of musculoskeletal pain. Lorzone is not a narcotic.
Fact Table |
Formula |
C7H4ClNO2 |
License |
US DailyMed |
Bioavailability |
Well absorbed |
Legal status |
Rx-Only |
Chemical Name |
Chlorzoxazone |
Elimination half-life |
1.1 hr Duration of action 3-4 hrs |
Dosage (Strength) |
375mg, 500mg, 750mg |
Pregnancy |
Consult Doctor |
Brands |
Lorzone |
Protein binding |
98% |
PubChem CID |
2733 |
MedlinePlus |
a682577 |
ChEBI |
3655 |
ATC code |
M03BB03 |
DrugBank |
DB00356 |
KEGG |
D00771 |
Routes of administration |
By mouth |
Directions
Lorzone is available in 250 mg, 375 mg, 500 mg, and 750 mg tablets.
The typical starting dose is 250 mg to 500 mg by mouth three to four times a day.
Ingredients
The active ingredient in Lorzone is chlorzoxazone.
Contraindications
Discuss your allergies with your doctor. Do not take Lorzone if you are allergic to chlorzoxazone or any other ingredient in Lorzone.
Cautions
- Lorzone may interact with certain medications. Tell your doctor about all the medications you take. These include prescription and over-the-counter medications as well as vitamins and herbal supplements.
- Tell your doctor about your health conditions.
- Lorzone can cause liver problems. Drinking alcohol or taking other medications that can cause central nervous system depression while being treated with Lorzone can further increase the risk.
- Tell your doctor if you are pregnant or plan to become pregnant.
- Tell your doctor if you are currently breastfeeding or plan to breastfeed.
Side Effects
Lorzone is generally tolerated well but can cause side effects such as drowsiness, dizziness, lightheadedness, overstimulation, gastrointestinal bleeding, or a feeling of general discomfort. Tell your doctor if you experience side effects that bother you or will not go away.
References:
- Lorzone Prescribing Information. Bridgewater, NJ: Vertical Pharmaceuticals, LLC; 2017.
- Chlorzoxazone (Lorzone). GoodRx. Last reviewed December 20, 2021. Accessed February 4, 2022.
Frequently Asked Questions about Lorzone (Chlorzoxazone)
What is Lorzone used for?
Lorzone is a muscle relaxant used to relieve pain and stiffness caused by muscle spasms. It's often used for conditions like back pain, neck pain, and pain from injuries.
How do I take Lorzone?
Take it by mouth, with or without food, as directed by your doctor. Don't take more than the prescribed dose or take it more often than advised.
What is the usual dosage?
The typical adult dose is 375mg three or four times daily. However, your doctor may adjust the dose based on your needs.
Can I take Lorzone with other medications?
Tell your doctor about all medications you're taking, including over-the-counter drugs and supplements. Some medicines can interact with Lorzone, increasing side effects.
Does Lorzone have side effects?
Yes, common side effects include drowsiness, dizziness, and headache. Less common, but serious, side effects can occur. Consult your doctor if you experience unusual symptoms.
Is Lorzone safe for everyone?
Tell your doctor about any existing medical conditions, especially liver disease, before taking Lorzone. It may not be suitable for everyone.
Is Lorzone addictive?
No, Lorzone is not considered addictive. However, it's important to follow your doctor's instructions and not take it for longer than recommended.
Can I drink alcohol while taking Lorzone?
Avoid alcohol while on Lorzone, as it can worsen drowsiness and dizziness.
Can I drive or operate machinery while taking Lorzone?
Use caution, as Lorzone can cause drowsiness and dizziness. Wait until you know how it affects you before engaging in activities requiring alertness.
What should I do if I miss a dose?
Take the missed dose as soon as possible, unless it's near the time for your next dose. Do not double up on doses.
About Dr. Savannah Muncy (Page Author)
Dr. Muncy (PharmD) studied science and education as an undergraduate before attending the Appalachian College of Pharmacy where she completed her PharmD in three years. She is currently using her pharmacy and healthcare expertise to write medical content for clients all around the world. She is focused on delivering the most current, accurate, and engaging information to healthcare professionals and patients. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 13597