Description
Lidex® (fluocinonide) Ointment 0.05% is a potent topical corticosteroid formulated for the relief of inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Fluocinonide exhibits anti-inflammatory, antipruritic, and vasoconstrictive properties, making it effective in reducing symptoms associated with various skin conditions.
Fact Table |
Formula | C26H32F2O6 |
License | US FDA |
Bioavailability | <1% (topical, intact skin) |
Legal status | Rx-only |
Chemical Name | Fluocinonide |
Elimination half-life | Unknown (minimal systemic absorption) |
Dosage (Strength) | 0.05% ointment |
Pregnancy | Category C – Use only if clearly needed |
Brands | Lidex, Lyderm, Fluonex, Topicon |
Protein binding | Unknown |
PubChem CID | 443975 |
MedlinePlus | a682799 |
ChEBI | 31499 |
ATC code | D07AC08 |
DrugBank | DB01013 |
KEGG | D00569 |
Routes of administration | Topical (skin) |
Directions
Apply a thin film of Lidex Ointment to the affected area two to four times daily, depending on the severity of the condition. Gently rub in the ointment until it is evenly distributed. Occlusive dressings may be used for the management of psoriasis or recalcitrant conditions; however, if an infection develops, discontinue the use of occlusive dressings and initiate appropriate antimicrobial therapy.
Ingredients
- Active Ingredient: Fluocinonide 0.05%.
- Inactive Ingredients: The specific inactive ingredients in Lidex Ointment are not detailed in the provided sources. For a comprehensive list, please refer to the product's packaging or consult the prescribing information.
Contraindications
Lidex Ointment is contraindicated in patients with:
- Untreated bacterial, tubercular, fungal, or viral infections of the skin, including herpes simplex, vaccinia, and varicella.
- Known hypersensitivity to fluocinonide or any components of the formulation.
Cautions
- Systemic Absorption: Topical corticosteroids can be absorbed in sufficient amounts to produce systemic effects, including reversible hypothalamic-pituitary-adrenal (HPA) axis suppression, manifestations of Cushing's syndrome, hyperglycemia, and glucosuria. Conditions that augment systemic absorption include the application of potent steroids, use over large surface areas, prolonged use, and the addition of occlusive dressings.
- Pediatric Use: Children may absorb proportionally larger amounts of topical corticosteroids and thus be more susceptible to systemic toxicity. Administration of topical corticosteroids to children should be limited to the least amount compatible with an effective therapeutic regimen. Chronic corticosteroid therapy may interfere with the growth and development of children.
- Local Adverse Reactions: Prolonged use may produce atrophy of the skin and subcutaneous tissues, particularly on flexor surfaces and on the face. If irritation develops, discontinue use and institute appropriate therapy.
Side Effects
The following local adverse reactions are reported infrequently with topical corticosteroids but may occur more frequently with the use of occlusive dressings:
- Allergic contact dermatitis
If any of these side effects occur, discontinue use and consult your healthcare provider.
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 1604