What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Leqvio (Inclisiran)
Prescription Required
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Product Details
Description
Leqvio (inclisiran) is an injectable medication that is prescribed with diet and statin therapy to treat primary hyperlipidemia, or elevated lipids in the blood, in adults.
Fact Table
Formula
C268H431N81O112P19S2
License
US FDA, EMA
Bioavailability
Subcutaneous: 48% (mean)
Legal status
Prescription only
Chemical Name
Inclisiran sodium
Elimination half-life
25-31 days
Dosage (Strength)
284 mg/1.5 mL (189 mg/mL)
Pregnancy
Consult a doctor
Brands
Leqvio
Protein binding
~86%
PubChem CID
122191593
MedlinePlus
a621033
ChEBI
CHEBI:163216
ATC code
C10AX13
DrugBank
DB15054
KEGG
D11465
Routes of administration
Subcutaneous
Directions
Leqvio is administered subcutaneously (underneath the skin) by a healthcare professional. You should receive an initial dose, then another dose at 3 months, and then every 6 months.
If you have any questions or concerns, talk to your doctor.
Ingredients
The active ingredient in Leqvio is inclisiran.
Contraindications
Leqvio should not be administered to patients who have ever had serious hypersensitivity to inclisiran or to any of the excipients in the medication.
Cautions
- Before you start receiving Leqvio injections, talk to your doctor about:
- All the prescription and over-the-counter medications you take
- Your allergies
- Your current health problems and past medical history
- Your pregnancy or breastfeeding status
Side Effects
Injection site reaction, joint pain, and bronchitis are common Leqvio side effects. However, other side effects may also occur.
Immediately tell your doctor about any side effects that bother you or persist.
Ask your doctor about Leqvio.
Reference
Leqvio. East Hanover, NJ: Novartis Pharmaceuticals Corporation; 2024.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 14449
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