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The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Leqvio (Inclisiran)

Brand

Leqvio (Inclisiran)

Prescription Required

Strength
Qty
284mg / 1.5ml
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  • Related Products & Conditions

  • Product Details

    Description

    Leqvio (inclisiran) is an injectable medication that is prescribed with diet and statin therapy to treat primary hyperlipidemia, or elevated lipids in the blood, in adults.

    Fact Table

    Formula

    C268H431N81O112P19S2

    License

    US FDA, EMA

    Bioavailability

    Subcutaneous: 48% (mean)

    Legal status

    Prescription only

    Chemical Name

    Inclisiran sodium

    Elimination half-life

    25-31 days

    Dosage (Strength)

    284 mg/1.5 mL (189 mg/mL)

    Pregnancy

    Consult a doctor

    Brands

    Leqvio

    Protein binding

    ~86%

    PubChem CID

    122191593

    MedlinePlus

    a621033

    ChEBI

    CHEBI:163216

    ATC code

    C10AX13

    DrugBank

    DB15054

    KEGG

    D11465

    Routes of administration

    Subcutaneous

    Directions

    Leqvio is administered subcutaneously (underneath the skin) by a healthcare professional. You should receive an initial dose, then another dose at 3 months, and then every 6 months.

    If you have any questions or concerns, talk to your doctor.

    Ingredients

    The active ingredient in Leqvio is inclisiran.

    Contraindications

    Leqvio should not be administered to patients who have ever had serious hypersensitivity to inclisiran or to any of the excipients in the medication.

    Cautions

    • Before you start receiving Leqvio injections, talk to your doctor about:
      • All the prescription and over-the-counter medications you take
      • Your allergies
      • Your current health problems and past medical history
      • Your pregnancy or breastfeeding status

    Side Effects

    Injection site reaction, joint pain, and bronchitis are common Leqvio side effects. However, other side effects may also occur.

    Immediately tell your doctor about any side effects that bother you or persist.

    Ask your doctor about Leqvio.

    Reference

    Leqvio. East Hanover, NJ: Novartis Pharmaceuticals Corporation; 2024.




    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 14449

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