Description
Indayo is a prescription oral contraceptive product for birth control, menstrual suppression, abnormal uterine bleeding, and other indications.
Fact Table |
Formula |
C21H28O2, C20H24O2 |
License |
US DailyMed, US FDA, EU EMA |
Bioavailability |
38% - 48% |
Legal status |
Rx-Only |
Chemical Name |
Levonogestrel and Ethinyl Estradiol |
Elimination half-life |
7–36 hours |
Dosage (Strength) |
120mcg/30mcg |
Pregnancy |
- |
Brands |
Indayo |
Protein binding |
97–98% |
PubChem CID |
13109, 5991 |
MedlinePlus |
a610021, a604032 |
ChEBI |
6443, 4903 |
ATC code |
G03AC03, G03CA01 |
DrugBank |
DB00367 |
KEGG |
D00950, D00554 |
Routes of administration |
By mouth |
Directions
Take one tablet by mouth once daily with or without food. The tablet should be taken at the same time every day.
Ingredients
The active ingredients are levonorgestrel and ethinyl estradiol.
Interactions
Drug-drug interactions may include:
- Ajmaline
- Anastrozole
- Anthrax Immune Globulin (Human)
- Antidiabetic Agents
- Aprepitant
- Asparaginase Products
- Atazanavir
- Bile Acid Sequestrants
- Brigatinib
- C1 inhibitors
- Carfilzomib
- Ivosidenib
- Ixazomib
- LamoTRIgine
- Lenalidomide
- Lixisenatide
- Lomitapide
- Mavacamten
- Melatonin
- MetyraPONE
- MiFEPRIStone
- Mivacurium
- Mobocertinib
- Mycophenolate
- Nirmatrelvir and Ritonavir
- Nonsteroidal Anti-Inflammatory Agents (COX-2 Selective)
- Octreotide
Cautions
Tell your doctors if you have a history of heart disease, liver problems, breast cancer, ovarian cancer, or are a current smoker.
Ask your pharmacist or doctor about all precautions that apply to you.
Side Effects
Common side effects may include:
- Abdominal cramps
- Abdominal pain
- Abnormal cervical or vaginal Papanicolaou smear
- Acne vulgaris
- Acute myocardial infarction
- Allergic skin rash
- Amenorrhea
- Application site reaction
- Arterial thromboembolism
- Auditory disturbance
- Bloating
- Breakthrough bleeding
- Breast changes
- Budd-Chiari syndrome
- Cataract
- Cerebral hemorrhage
- Cerebral thrombosis
- Cerebrovascular accident
- Cervical ectropion
- Cervical erosion
- Change in appetite
- Change in cervical secretions
- Change in corneal curvature
- Change in libido
- Change in menstrual flow
- Changes in serum lipids
- Chloasma
- Cholecystitis
- Cholelithiasis
- Cholestatic jaundice
- Colitis
- Contact lens intolerance
- Cystitis-like syndrome
- Decreased serum folate level
- Deep vein thrombosis
- Depression
- Dizziness
- Dysmenorrhea
- Ectopic pregnancy
- Edema
- Endocervical hyperplasia
- Erythema multiforme
- Erythema nodosum
- Exacerbation of porphyria
- Exacerbation of systemic lupus erythematosus
- Exacerbation of tics
- Fluid retention
- Gallbladder disease
- Headache
- Hemolytic-uremic syndrome
- Hemorrhagic eruption
- Hepatic adenoma
- Hepatic focal nodular hyperplasia
- Hepatic neoplasm (benign)
- Hirsutism
- Hypertension
- Impaired glucose tolerance/prediabetes
- Infertility (temporary)
- Infrequent uterine bleeding
- Lactation insufficiency (with use immediately postpartum)
- Local thrombophlebitis
- Loss of scalp hair
- Major depressive disorder
- Mesenteric thrombosis
- Migraine
- Mood changes
- Nausea
- Nervousness
- Nonimmune anaphylaxis
- Optic neuritis
- Pancreatitis
- Premenstrual syndrome
- Pulmonary embolism
- Renal insufficiency
- Retinal thrombosis
- Rhinitis
- Spotting
- Suicidal ideation
- Uterine fibroid enlargement
- Vaginitis
- Venous thromboembolism
- Venous thrombosis
- Vomiting
- Vulvovaginal candidiasis
- Weight changes
- Weight gain
- Worsening of varicose veins
References
- Indayo [Product Monograph]. Etobicoke, ON: Mylan Pharmaceuticals; 2016.
About Dr. Conor Sheehy (Page Author)
Dr. Sheehy (BSc Molecular Biology, PharmD) works a clinical pharmacist specializing in cardiology, oncology, and ambulatory care. He’s a board-certified pharmacotherapy specialist (BCPS), and his experience working one-on-one with patients to fine tune their medication and therapy plans for optimal results makes him a valuable subject matter expert for our pharmacy. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 13909