Description
Incruse Ellipta is an inhaled medication that is used to treat Chronic Obstructive Pulmonary Disease (COPD). COPD is a group of chronic diseases that includes chronic bronchitis and emphysema.
The symptoms of COPD are progressive and can include shortness of breath, chronic cough, and wheezing.
Incruse Ellipta works by stopping acetylcholine, a neurotransmitter, from activating muscarinic receptors in the smooth muscle of the lungs. This effect causes bronchodilation, which is the relaxation of the airways, and makes it easier to breathe.
Fact Table |
Formula |
C29H34BrNO2 |
License |
EU EMA |
Bioavailability |
13% |
Legal status |
Rx-only |
Chemical Name |
Umeclidinium |
Elimination half-life |
11 hours |
Dosage (Strength) |
55mcg |
Pregnancy |
Consult Doctor |
Brands |
Incruse Ellipta |
Protein binding |
~89% |
PubChem CID |
11519069 |
MedlinePlus |
a614024 |
ChEBI |
79040 |
ATC code |
R03BB07 |
DrugBank |
DB09076 |
KEGG |
D10181 |
Routes of administration |
Inhalation |
Directions
The standard dosage of Incruse Ellipta inhaler is one inhalation once daily.
Incruse Ellipta is a maintenance medication, meaning it must be taken every day to be effective.
Ingredients
The active ingredient in Incruse Ellipta is called umeclidinium.
Interactions
- Aclidinium
- Amantadine
- Atropine
- Benztropine
- Botulinum Toxin-Containing Products
- Chloral Betaine
- Chlorthalidone
- Darifenacin
- Dicyclomine
- Fesoterodine
- Gastrointestinal Agents
- Glucagon
- Glycopyrrolate
- Hydrochlorothiazide
- Hyoscyamine
- Ipratropium
- Mirabegron
- Nitroglycerin
- Oxybutynin
- Potassium Chloride
- Scopolamine
- Solifenacin
- Tiotropium
- Tolterodine
- Topiramate
- Trihexyphenidyl
- Trospium
Cautions
Do not use Incruse Ellipta if you have an allergy to milk proteins.
Incruse Ellipta cannot be used to treat acute symptoms of COPD or for acutely worsening patients. Acute symptoms should be treated with a rescue inhaler like albuterol.
Tell your doctor if you have a history of narrow-angle glaucoma before starting this medication.
Incruse Ellipta can worsen urinary retention in some people.
Side Effects
Every medication has a list of potential side effects. Common Incruse Ellipta side effects can include:
- Arthralgia
- Blurred vision
- Bruise
- Cough
- Dysgeusia
- Dysuria
- Eye pain
- Glaucoma
- Myalgia
- Nasopharyngitis
- Pharyngitis
- Tachycardia
- Toothache
- Upper abdominal pain
- Upper respiratory infection
- Urinary retention
- Viral upper respiratory tract infection
Speak with your doctor and pharmacist about any side effects you experience while using this inhaler.
References
- Incruse Ellipta [package insert]. Research Triangle Park, NC: GlaxoSmithKline; 2016.
Frequently Asked Questions about Incruse Ellipta
What is Incruse Ellipta?
Incruse Ellipta is a prescription medication used to treat chronic obstructive pulmonary disease (COPD). It contains the active ingredient umeclidinium, which helps to relax the muscles in the airways and improve breathing in individuals with COPD.
How does Incruse Ellipta work?
Incruse Ellipta works by relaxing the muscles in the airways, making it easier for individuals with COPD to breathe. It helps to prevent symptoms like shortness of breath, coughing, and wheezing.
What is the recommended dosage of Incruse Ellipta?
The recommended dosage of Incruse Ellipta is typically one inhalation once daily. However, the specific dosing instructions may vary based on your individual medical condition and the advice of your healthcare provider. It is important to follow your healthcare provider's instructions carefully.
Are there any side effects associated with Incruse Ellipta?
Yes, like any medication, Incruse Ellipta can have side effects. Common side effects may include headache, cough, dry mouth, and throat irritation. It's important to discuss potential side effects with your healthcare provider and report any unusual or severe side effects promptly.
How long does it take for Incruse Ellipta to start working?
The onset of action may vary from person to person, but some individuals may start to experience improved breathing within a few days of starting Incruse Ellipta. However, it may take several weeks for the full benefits of the medication to be realized.
Can Incruse Ellipta be used as a rescue inhaler?
No, Incruse Ellipta is not a rescue inhaler. It is a maintenance medication used to manage and control the symptoms of COPD over the long term. It should not be used to relieve sudden breathing problems; for that purpose, a separate rescue inhaler may be prescribed by your healthcare provider.
Can I use Incruse Ellipta if I have other medical conditions or take other medications?
It's essential to inform your healthcare provider about all your medical conditions and medications you are taking before starting Incruse Ellipta. They can determine if it is safe and suitable for you. Some medications or medical conditions may interact with Incruse Ellipta.
How should I store Incruse Ellipta?
Incruse Ellipta should be stored at room temperature, away from moisture, heat, and direct sunlight. Keep it out of the reach of children, and always follow the storage instructions provided with the medication.
Can I stop taking Incruse Ellipta if my COPD symptoms improve?
No, you should not stop taking Incruse Ellipta without consulting your healthcare provider. It is a maintenance medication meant to be used regularly to manage your COPD. Stopping it abruptly could lead to a worsening of your symptoms.
How can I get a prescription for Incruse Ellipta?
You can only obtain Incruse Ellipta with a prescription from a licensed healthcare provider. If you believe it may be a suitable treatment for your COPD, schedule an appointment with your healthcare provider to discuss your symptoms and treatment options.
About Dr. Conor Sheehy (Page Author)
Dr. Sheehy (BSc Molecular Biology, PharmD) works a clinical pharmacist specializing in cardiology, oncology, and ambulatory care. He’s a board-certified pharmacotherapy specialist (BCPS), and his experience working one-on-one with patients to fine tune their medication and therapy plans for optimal results makes him a valuable subject matter expert for our pharmacy. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 13204