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Humira (Adalimumab)

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  • Product Details

    Description

    Humira is a type of medication called a monoclonal antibody. It is a prescription drug that can target specific proteins in the body that lead to autoimmune disease. The following conditions can be treated with Humira:

    • Ankylosing spondylitis
    • Crohn disease
    • Hidradenitis suppurativa
    • Plaque psoriasis
    • Psoriatic arthritis
    • Rheumatoid arthritis
    • Ulcerative colitis
    • Uveitis

    Humira works by binding to TNF-alpha, a protein free-floating in the blood. Normally, TNF-alpha activates many different immune system cells. For people with the above conditions, they have too much activity in their immune system. Humira helps to lower that activity back to normal.

    Fact Table

    Formula

    C6428H9912N1694O1987S46

    License

    US FDA, EU EMA

    Bioavailability

    64%

    Legal status

    Rx-Only

    Chemical Name

    Adalimumab

    Elimination half-life

    3 hour

    Dosage (Strength)

    -

    Pregnancy

    not recommended

    Brands

    Humira

    Protein binding

    Not Available

    PubChem CID

    Not Available

    MedlinePlus

    a603010

    ChEBI

    Not Available

    ATC code

    L04AB04

    DrugBank

    DB00051

    KEGG

    D02597

    Routes of administration

    Subcutaneous

    Directions

    The directions for Humira are determined by your healthcare provider. The Humira dosage varies based on what condition is being treated.

    Use Humira exactly as prescribed by your healthcare provider.

    Humira should be stored in the refrigerator at 36°F to 46°F (2°C to 8°C), and not in the freezer. If brought to room temperature, Humira will last for 14 days.

    Ingredients

    Adalimumab is the active ingredient in Humira.

    Interactions

    Serious drug-drug interactions with Humira include:

    • Abatacept
    • Anakinra
    • BCG
    • Certolizumab
    • Echinacea
    • Fingolimod
    • Inactivated vaccines
    • Leflunomide
    • Live vaccines
    • Natalizumab
    • Pimecrolimus
    • Sipuleucel-T
    • Tacrolimus
    • Tocilizumab
    • Vedolizumab

    Cautions

    Tell your doctor if you have a history of cardiovascular disease or heart failure before taking Humira.

    Tell your doctor if you have a latent infection like hepatitis B or tuberculosis. Humira can reactivate these infections.

    Humira may increase the risk of certain cancers.

    This list is not a full list of the possible precautions while taking Humira. Ask your doctor or pharmacist for precautions that are applicable to you.

    Side Effects

    Common Humira side effects may include:

    • Antibody development
    • Headache
    • Increase creatinine phosphokinase
    • Infections
    • Injection site reaction
    • Positive autoantibody titer
    • Sinusitis
    • Skin rash
    • Upper respiratory tract infection

    References

    1. Humira [package insert].Chicago, IL: Abbvie; 2020.

    Frequently Asked Questions about Humira (Adalimumab)


    What is Humira (Adalimumab)?

    Humira (Adalimumab) is a prescription medication used to treat various autoimmune conditions, including rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, ulcerative colitis, plaque psoriasis, and more. It belongs to a class of drugs called TNF blockers.


    How does Humira work?

    Humira works by targeting and neutralizing a protein called tumor necrosis factor alpha (TNF-alpha). TNF-alpha plays a key role in inflammation, and by blocking it, Humira helps reduce inflammation and alleviate symptoms associated with autoimmune diseases.


    What conditions are treated with Humira?

    Humira is prescribed to manage and treat autoimmune conditions such as rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, ulcerative colitis, hidradenitis suppurativa, juvenile idiopathic arthritis, plaque psoriasis, and more. It is important to consult with a healthcare provider to determine if Humira is the right treatment for your specific condition.


    How is Humira administered?

    Humira is typically administered by subcutaneous injection (under the skin). The frequency of injections and dosage can vary depending on the condition being treated. Healthcare providers will provide detailed instructions on how to administer the medication.


    Are there any potential side effects of Humira?

    Common side effects of Humira may include injection site reactions, headache, upper respiratory infections, and rash. However, more serious side effects, such as infections or allergic reactions, can occur. It's essential to discuss potential side effects with your healthcare provider.


    Can Humira be used during pregnancy or while breastfeeding?

    The use of Humira during pregnancy and breastfeeding should be discussed with a healthcare provider. It's important to weigh the potential benefits against the risks, as the safety of Humira during these periods is not fully understood.


    Is Humira safe for long-term use?

    Humira may be prescribed for both short-term and long-term use, depending on the condition being treated. It is essential to follow your healthcare provider's guidance and undergo regular check-ups to monitor your response to the medication.


    Can I drink alcohol while taking Humira?

    Moderate alcohol consumption is generally considered safe while taking Humira. However, it's advisable to consult with your healthcare provider regarding alcohol consumption, as excessive alcohol intake can impact your overall health and well-being.


    Where can I obtain Humira?

    Humira is available by prescription only. To obtain Humira, you'll need to consult with a healthcare provider, such as a rheumatologist or gastroenterologist, who can evaluate your condition and determine if Humira is an appropriate treatment option.


    Can Humira be used in combination with other medications?

    Humira may be used in combination with other medications as part of a treatment plan. However, the specific combination of medications should be discussed with your healthcare provider to ensure safety and effectiveness.




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    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 2593

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