What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Grifulvin V (Griseofulvin)
Also Known as Grisovin
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Product Details
Description
Grifulvin V is a prescription medication used to treat dermatophyte infections, a type of fungal infection of the skin. Other terms for this condition include dermatophytosis or tinea, which affect the nails, hair, and skin.
Symptoms of dermatophyte infection depend on where they are located and can include rashes, scaling, and itching.
Grifulvin V works by stopping the growth and replication of fungal cells. Grifulvin V also binds to keratin in human skin, making it resistant to fungal infection.
Fact Table
Formula
C17H17ClO6
License
US FDA
Bioavailability
25 to 70%
Legal status
Rx-Only
Chemical Name
Griseofulvin
Elimination half-life
9–21 hours
Dosage (Strength)
500mg
Pregnancy
Consult Doctor
Brands
Gris-peg, Grifulvin V
Protein binding
84%
PubChem CID
441140
MedlinePlus
a682295
ChEBI
27779
ATC code
D01AA08
DrugBank
DB00400
KEGG
D00209
Routes of administration
By mouth
Directions
The standard dosage is 500 mg in single or divided doses. Your doctor may increase the dose to 750-1000 mg per day if needed for widespread infections.
Ingredients
The active ingredient and name for Grifulvin V generic is griseofulvin.
Interactions
Common drug-drug interactions with this medication may include:
- Alcohol
- Aminolevulinic Acid
- Barbiturates
- Carbocisteine
- Cyclosporine
- Hormonal contraceptives
- Saccharomyces boulardii
- Warfarin
Tell your healthcare team if you are taking any of the above medications before starting Grifulvin V.Cautions
Tell your doctor if you have a history of blood disorders. Grifulvin V has been rarely reported to cause leukopenia.
Use caution if you have a history of liver problems before taking this medication.
If you have a history of allergic reactions to penicillin, use caution before taking Grifulvin V.
Wear sunscreen while taking this medication because it can increase the sensitivity to the sun.
Call your doctor immediately if you have a skin reaction after starting this drug.
Side Effects
Grifulvin V side effects may include:
- Angioedema
- Confusion
- Dermatologic reaction
- Diarrhea
- Dizziness
- Epigastric distress
- Fatigue
- Gastrointestinal hemorrhage
- Granulocytopenia
- Headache
- Hepatotoxicity
- Increased liver enzymes
- Increased serum bilirubin
- Insomnia
- Nausea
- Nephrosis
- Oral candidiasis
- Paresthesia
- Skin photosensitivity
- Skin rash
- Toxic epidermal necrolysis
- Urticaria
- Vomiting
References
- Grifulvin V [package insert]. Los Angeles, CA: Ortho Dermatologics; 2011.
Frequently Asked Questions about Grifulvin V (Griseofulvin)
What is Grifulvin V (Griseofulvin)?
Grifulvin V, with the active ingredient Griseofulvin, is an antifungal medication used to treat fungal infections of the skin, hair, and nails. It belongs to a class of drugs known as antifungals.
How does Grifulvin V work to treat fungal infections?
Grifulvin V works by inhibiting the growth and reproduction of fungi. It interferes with the fungal cell's ability to divide and multiply, ultimately leading to the elimination of the infection.
What types of fungal infections can Grifulvin V treat?
Grifulvin V is commonly prescribed to treat fungal infections of the skin, such as ringworm (tinea corporis), athlete's foot (tinea pedis), and fungal infections of the scalp and nails (tinea capitis and onychomycosis).
Is Grifulvin V available over the counter (OTC)?
No, Grifulvin V is not available over the counter. It is a prescription medication, which means you need a doctor's prescription to obtain it.
How should I take Grifulvin V?
Follow your doctor's instructions carefully. Grifulvin V is usually taken orally with a fatty meal to improve absorption. The dosage and duration of treatment will depend on the type and severity of the fungal infection.
What are the potential side effects of using Grifulvin V?
Common side effects may include headache, upset stomach, diarrhea, and skin rashes. Less commonly, it can cause liver problems and blood disorders. If you experience severe side effects, contact your healthcare provider.
Can I take other medications while using Grifulvin V?
Inform your healthcare provider about all medications, supplements, and herbal products you are taking, as they may interact with Grifulvin V. Your doctor will assess potential drug interactions.
Is Grifulvin V a cure for fungal infections?
Grifulvin V is used to treat fungal infections effectively, but it is not a permanent cure. It eliminates the current infection, but reinfection can occur if you are exposed to the fungi again.
Can I consume alcohol while taking Grifulvin V?
It is generally advisable to avoid alcohol while taking Grifulvin V, as it can increase the risk of certain side effects, particularly liver problems. Consult your healthcare provider for specific guidance.
How long will I need to take Grifulvin V?
The duration of Grifulvin V treatment depends on the type and severity of the fungal infection. Your healthcare provider will determine the appropriate length of treatment, which can vary from a few weeks to several months.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 2769
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