Glyset (Miglitol)
What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
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Prescription Required
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Product Details
Description
Glyset (miglitol) is used with diet and exercise to help treat type 2 diabetes in adults.
Glyset is available in 25 mg, 50 mg, and 100 mg oral tablets.
Fact Table
Formula
C8H17NO5
License
US FDA
Bioavailability
~3.2% (low)
Legal status
Prescription only (Rx)
Chemical Name
(2R,3R,4R,5S)-1-(Hydroxymethyl)-2-(hydroxymethyl)-3,4,5-piperidinetriol
Elimination half-life
2 hours
Dosage (Strength)
25 mg, 50 mg, 100 mg tablets
Pregnancy
Consult a doctor
Brands
Glyset
Protein binding
Negligible
PubChem CID
441314
MedlinePlus
a696005
ChEBI
CHEBI:50692
ATC code
A10BF03
DrugBank
DB00491
KEGG
D08110
Routes of administration
Oral
Directions
Take Glyset exactly as prescribed by your doctor, who will determine an appropriate dose for you.
The recommended starting dose is 25 mg by mouth three times a day at the beginning of meals. The dose may be gradually increased as necessary by your doctor.
For further instructions for use, refer to the medication guide that accompanies your Glyset prescription.
Keep Glyset at 25°C (77°F) and away from children.
If you have any questions or concerns about the medication, speak with your doctor or pharmacist.
Ingredients
The active ingredient in Glyset is miglitol.
Inactive ingredients include starch, microcrystalline cellulose, magnesium stearate, hypromellose, polyethylene glycol, titanium dioxide, and polysorbate 80.
Contraindications
Patients who are allergic to Glyset or who have diabetic ketoacidosis, inflammatory bowel disease, partial intestinal obstruction, colonic ulceration, or who are predisposed to intestinal obstruction should not take Glyset.
Patients with chronic intestinal diseases associated with marked absorption or digestive disorders, or with conditions that can deteriorate from increased gas formation in the intestine should also not take Glyset.
Cautions
- Before you begin taking Glyset, talk to your doctor about:
- All the prescription and over-the-counter medications you take
- Your allergies
- Your current health problems and past medical history
- Your pregnancy or breastfeeding status
- Glyset is associated with the following precautions:
- Low blood glucose levels
- Loss of blood glucose control with exposure to stressful situations (e.g., fever, trauma, surgery, infection) that may require temporary insulin therapy
- Kidney problems
- Glyset should only be used in pregnant women only if the benefits outweigh the risks.
- Breastfeeding is not recommended.
Side Effects
Diarrhea, stomach pain, gas, and skin rash are possible Glyset medication side effects; however, other side effects can also occur. Immediately inform your doctor of any side effects that bother you or won’t go away.
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Reference
Glyset. New York, NY: Bayer HealthCare Pharmaceuticals Inc.; 2023.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 9729
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