Description
Glyset (miglitol) is used with diet and exercise to help treat type 2 diabetes in adults.
Glyset is available in 25 mg, 50 mg, and 100 mg oral tablets.
Fact Table
|
Formula
|
C8H17NO5
|
License
|
US FDA
|
Bioavailability
|
~3.2% (low)
|
Legal status
|
Prescription only (Rx)
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Chemical Name
|
(2R,3R,4R,5S)-1-(Hydroxymethyl)-2-(hydroxymethyl)-3,4,5-piperidinetriol
|
Elimination half-life
|
2 hours
|
Dosage (Strength)
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25 mg, 50 mg, 100 mg tablets
|
Pregnancy
|
Consult a doctor
|
Brands
|
Glyset
|
Protein binding
|
Negligible
|
PubChem CID
|
441314
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MedlinePlus
|
a696005
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ChEBI
|
CHEBI:50692
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ATC code
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A10BF03
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DrugBank
|
DB00491
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KEGG
|
D08110
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Routes of administration
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Oral
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Directions
Take Glyset exactly as prescribed by your doctor, who will determine an appropriate dose for you.
The recommended starting dose is 25 mg by mouth three times a day at the beginning of meals. The dose may be gradually increased as necessary by your doctor.
For further instructions for use, refer to the medication guide that accompanies your Glyset prescription.
Keep Glyset at 25°C (77°F) and away from children.
If you have any questions or concerns about the medication, speak with your doctor or pharmacist.
Ingredients
The active ingredient in Glyset is miglitol.
Inactive ingredients include starch, microcrystalline cellulose, magnesium stearate, hypromellose, polyethylene glycol, titanium dioxide, and polysorbate 80.
Contraindications
Patients who are allergic to Glyset or who have diabetic ketoacidosis, inflammatory bowel disease, partial intestinal obstruction, colonic ulceration, or who are predisposed to intestinal obstruction should not take Glyset.
Patients with chronic intestinal diseases associated with marked absorption or digestive disorders, or with conditions that can deteriorate from increased gas formation in the intestine should also not take Glyset.
Cautions
- Before you begin taking Glyset, talk to your doctor about:
- All the prescription and over-the-counter medications you take
- Your allergies
- Your current health problems and past medical history
- Your pregnancy or breastfeeding status
- Glyset is associated with the following precautions:
- Low blood glucose levels
- Loss of blood glucose control with exposure to stressful situations (e.g., fever, trauma, surgery, infection) that may require temporary insulin therapy
- Kidney problems
- Glyset should only be used in pregnant women only if the benefits outweigh the risks.
- Breastfeeding is not recommended.
Side Effects
Diarrhea, stomach pain, gas, and skin rash are possible Glyset medication side effects; however, other side effects can also occur. Immediately inform your doctor of any side effects that bother you or won’t go away.
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Reference
Glyset. New York, NY: Bayer HealthCare Pharmaceuticals Inc.; 2023.
About Dr. Savannah Muncy (Page Author)
Dr. Muncy (PharmD) studied science and education as an undergraduate before attending the Appalachian College of Pharmacy where she completed her PharmD in three years. She is currently using her pharmacy and healthcare expertise to write medical content for clients all around the world. She is focused on delivering the most current, accurate, and engaging information to healthcare professionals and patients. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 9729