What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Follistim AQ
Also Known as Puregon in Canada
Prescription Required
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Product Details
Description
Follistim AQ (follitropin beta injection) is a prescription medication used to treat infertility in men and women. It contains a hormone called follicle-stimulating hormone (FSH), which helps stimulate the development of follicles in the ovaries and spermatogenesis in the testes.
Follistim AQ is available in a prefilled pen and is administered by injection under the skin.
Fact Table
Formula
C975H1513N267O304S26
License
US FDA
Bioavailability
77%
Legal status
Rx-Only
Chemical Name
Follitropin beta
Elimination half-life
26.9–43.9 h
Dosage (Strength)
-
Pregnancy
Contraindicated
Brands
Follistim AQ
Protein binding
Not available
PubChem CID
Not available
MedlinePlus
Not available
ChEBI
Not available
ATC code
G03GA05
DrugBank
DB00066
KEGG
D04430
Routes of administration
Subcutaneous injection
Directions
Your dosage and frequency will depend on various factors, including what condition you are treating.
For women, Follistim AQ is typically injected subcutaneously once daily with a slowly increasing dose based on response.
For men, Follistim AQ is usually injected two or three times weekly in combination with hCG for at least 3-4 months.
Ingredients
The active ingredient in Follistim AQ is follitropin beta, a recombinant form of FSH produced using genetic engineering technology.
Interactions
- There are no known significant interactions.
Cautions
Tell your doctor if you have a history of ovarian cysts, uterine fibroids, endometriosis, or other conditions that may be affected by hormonal changes.
Follistim AQ may increase the risk of multiple pregnancies, which can be associated with increased health risks for both the mother and infants.
Your doctor will closely monitor the ovarian response to Follistim AQ, as excessive stimulation can lead to ovarian hyperstimulation syndrome (OHSS). Symptoms of OHSS include abdominal pain, bloating, nausea, and vomiting.
Side Effects
The most common adverse effects of this drug include the following:
- Abdominal distension
- Abdominal distress
- Abdominal pain
- Acne vulgaris
- Breast tenderness
- Constipation
- Dermoid cyst
- Diarrhea
- Fatigue
- Gynecomastia
- Headache
- Injection site reaction
- Lower abdominal pain
- Nausea
- Ovarian cyst
- Ovarian hyperstimulation
- Ovarian neoplasm
- Ovarian torsion
- Ovary enlargement
- Pain at the injection site
- Pelvic discomfort
- Pelvic pain
- Skin rash
- Spontaneous abortion
- Thromboembolism
- Uterine hemorrhage
- Vaginal hemorrhage
If you experience any of the above, tell your healthcare team immediately.
References
Follistim AQ [package insert]. West Orange, NJ: Organon USA Inc.; 2004.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 10149
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